The avengers: SAMHD1 cooperates with MX2/MxB to defend against HIV-1
ABSTRACT SAMHD1 is an intrinsic limiting factor that effectively prevents HIV-1 infection in macrophages, dendritic cells, and resting CD4+ T cells. Extensive studies have underscored the indispensable role of the dNTPase activity of SAMHD1 in its antiviral function by primarily depleting dNTPs in q...
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Fformat: | Erthygl |
Iaith: | English |
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American Society for Microbiology
2024-10-01
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Cyfres: | mBio |
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Mynediad Ar-lein: | https://journals.asm.org/doi/10.1128/mbio.01675-24 |