Comparison of fibroblast-growth factor-23 level between males and female’s broiler using HPLC technique
Animal public health is crucial concern when considering the role of fibroblast growth factor-23 (FGF-23) in regulating phosphate metabolism. FGF-23 has been associated with to various diseases in animal, such as chronic kidney and cardiovascular disease, making it a crucial factor to consider for m...
| Main Authors: | , |
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| Format: | Article |
| Language: | Arabic |
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University of Mosul, College of Veterinary Medicine
2023-10-01
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| Series: | Iraqi Journal of Veterinary Sciences |
| Subjects: | |
| Online Access: | https://www.vetmedmosul.com/article_180612_24e3bba806ef3478a8a949bc3480c9b9.pdf |
| _version_ | 1827802441489317888 |
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| author | Soulaf J. Kakel Ayman M. Albanna |
| author_facet | Soulaf J. Kakel Ayman M. Albanna |
| author_sort | Soulaf J. Kakel |
| collection | DOAJ |
| description | Animal public health is crucial concern when considering the role of fibroblast growth factor-23 (FGF-23) in regulating phosphate metabolism. FGF-23 has been associated with to various diseases in animal, such as chronic kidney and cardiovascular disease, making it a crucial factor to consider for maintaining the well-being of animals and ensuring public health. This study aimed to measure the levels of FGF-23 protein in broiler chickens and compare them to a standard level of 375 pg/ml. Blood samples were collected from 10 female and 10 male broiler chickens, and FGF-23 protein levels were analyzed using high-performance liquid chromatography (HPLC). The results showed significant gender differences in FGF-23 protein levels, with males having a higher level of FGF-23 protein than females. Females had a mean level of 256.12 pg/ml (SD = 86.02), while males had a significantly higher mean level of 1508.71 pg/mL (SD = 1113.85). However, the study is limited by the small sample size and the use of a single population. Further research with larger and more diverse samples is needed to confirm the generalizability of these findings. Conclusion, this study provides important insights into the role of gender in FGF-23 protein metabolism in broiler chickens, and may have implications for the diagnosis and treatment of diseases associated with FGF-23 protein dysregulation in poultry. |
| first_indexed | 2024-03-11T20:39:58Z |
| format | Article |
| id | doaj.art-10f308eb6a724e5ebd70fe45ef195721 |
| institution | Directory Open Access Journal |
| issn | 1607-3894 2071-1255 |
| language | Arabic |
| last_indexed | 2024-03-11T20:39:58Z |
| publishDate | 2023-10-01 |
| publisher | University of Mosul, College of Veterinary Medicine |
| record_format | Article |
| series | Iraqi Journal of Veterinary Sciences |
| spelling | doaj.art-10f308eb6a724e5ebd70fe45ef1957212023-10-02T03:07:56ZaraUniversity of Mosul, College of Veterinary MedicineIraqi Journal of Veterinary Sciences1607-38942071-12552023-10-0137495796110.33899/ijvs.2023.138455.2803180612Comparison of fibroblast-growth factor-23 level between males and female’s broiler using HPLC techniqueSoulaf J. Kakel0Ayman M. Albanna1Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Mosul, Mosul, IraqDepartment of Environmental Sciences, College of Environmental Sciences and Technologies, University of Mosul, Mosul, IraqAnimal public health is crucial concern when considering the role of fibroblast growth factor-23 (FGF-23) in regulating phosphate metabolism. FGF-23 has been associated with to various diseases in animal, such as chronic kidney and cardiovascular disease, making it a crucial factor to consider for maintaining the well-being of animals and ensuring public health. This study aimed to measure the levels of FGF-23 protein in broiler chickens and compare them to a standard level of 375 pg/ml. Blood samples were collected from 10 female and 10 male broiler chickens, and FGF-23 protein levels were analyzed using high-performance liquid chromatography (HPLC). The results showed significant gender differences in FGF-23 protein levels, with males having a higher level of FGF-23 protein than females. Females had a mean level of 256.12 pg/ml (SD = 86.02), while males had a significantly higher mean level of 1508.71 pg/mL (SD = 1113.85). However, the study is limited by the small sample size and the use of a single population. Further research with larger and more diverse samples is needed to confirm the generalizability of these findings. Conclusion, this study provides important insights into the role of gender in FGF-23 protein metabolism in broiler chickens, and may have implications for the diagnosis and treatment of diseases associated with FGF-23 protein dysregulation in poultry.https://www.vetmedmosul.com/article_180612_24e3bba806ef3478a8a949bc3480c9b9.pdfanimal public healthfibroblast growth factor-23broiler |
| spellingShingle | Soulaf J. Kakel Ayman M. Albanna Comparison of fibroblast-growth factor-23 level between males and female’s broiler using HPLC technique Iraqi Journal of Veterinary Sciences animal public health fibroblast growth factor-23 broiler |
| title | Comparison of fibroblast-growth factor-23 level between males and female’s broiler using HPLC technique |
| title_full | Comparison of fibroblast-growth factor-23 level between males and female’s broiler using HPLC technique |
| title_fullStr | Comparison of fibroblast-growth factor-23 level between males and female’s broiler using HPLC technique |
| title_full_unstemmed | Comparison of fibroblast-growth factor-23 level between males and female’s broiler using HPLC technique |
| title_short | Comparison of fibroblast-growth factor-23 level between males and female’s broiler using HPLC technique |
| title_sort | comparison of fibroblast growth factor 23 level between males and female s broiler using hplc technique |
| topic | animal public health fibroblast growth factor-23 broiler |
| url | https://www.vetmedmosul.com/article_180612_24e3bba806ef3478a8a949bc3480c9b9.pdf |
| work_keys_str_mv | AT soulafjkakel comparisonoffibroblastgrowthfactor23levelbetweenmalesandfemalesbroilerusinghplctechnique AT aymanmalbanna comparisonoffibroblastgrowthfactor23levelbetweenmalesandfemalesbroilerusinghplctechnique |