Effects of Hypocalcemic Vitamin D Analogs in the Expression of DNA Damage Induced in Minilungs from hESCs: Implications for Lung Fibrosis

Effects of Hypocalcemic Vitamin D Analogs in the Expression of DNA Damage Induced in Minilungs from hESCs: Implications for Lung Fibrosis

In our previous work, we evaluated the therapeutic effects of 1α,25-Dihydroxyvitamin D<sub>3</sub>, the biologically active form of vitamin D, in the context of bleomycin-induced lung fibrosis. Contrary to the expected, vitamin D supplementation increased the DNA damage expression and ce...

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Bibliographic Details
Main Authors: Esmeralda Magro-Lopez, Irene Chamorro-Herrero, Alberto Zambrano
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
human pluripotent stem cells
hESCs
minilungs
vitamin D
vitamin D analogs
paricalcitol
Online Access:https://www.mdpi.com/1422-0067/23/9/4921

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