Comparison of Osteoimmunological and Microbiological Parameters of Extra Short and Longer Implants Loaded in the Posterior Mandible: A Split Mouth Randomized Clinical Study
Objectives: This study aimed to evaluate the levels of TNF-α, PGE2, RANKL, RANK, OPG, the markers of periimplant bone loss in peri-implant crevicular fluid obtained around standard and extra short implants. Moreover, the levels of putative oral pathogens were investigated in the submucosal biofilm s...
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| Format: | Article |
| Language: | English |
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University of Zagreb. School of Dental Medicine
2021-01-01
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| Series: | Acta Stomatologica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/381568 |
| _version_ | 1797206908247998464 |
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| author | Bilge Karci Elif Oncu |
| author_facet | Bilge Karci Elif Oncu |
| author_sort | Bilge Karci |
| collection | DOAJ |
| description | Objectives: This study aimed to evaluate the levels of TNF-α, PGE2, RANKL, RANK, OPG, the markers of periimplant bone loss in peri-implant crevicular fluid obtained around standard and extra short implants. Moreover, the levels of putative oral pathogens were investigated in the submucosal biofilm samples. Material and Methods: The implants were divided into two groups according to their lengths: standard (≥8 mm) and extra short (4 mm). A total of 60 implants were researched in 30 patients. The probing depth (PD), clinical attachment level (CAL), presence of bleeding on probing (BOP), 3-year survival rate (CSR), and bone loss (BL) were measured. Results: No statistically significant difference was found in the values of PD, CAL, BOP, CSR, and BL between the groups (P> 0.05). Total amounts of PGE2, TNF-α, RANKL, RANK, OPG, and RANKL/OPG were not statistically significantly different between the groups (P> 0.05). The abundance of F. nucleatum, T. forsythia, P. intermedia, P. gingivalis, S. oralis and T. denticola was compared between the groups and the results were not statistically significant (P> 0.05). Conclusion: The results of this study suggested that PGE2, TNF-α, RANKL, RANK, OPG, and RANKL/OPG in PICF, as well as microbiological parameters in submucosal
biofilms, were similar between standard (≥8 mm) and extra short (4 mm) implants. Therefore, the implant length does not seem to influence the bone loss, levels of osteoimmunological and microbiological markers in the peri-implant tissues and survival rates. |
| first_indexed | 2024-04-24T09:14:29Z |
| format | Article |
| id | doaj.art-10ff51e814e445ce8f2d8ae2bb7f5391 |
| institution | Directory Open Access Journal |
| issn | 0001-7019 1846-0410 |
| language | English |
| last_indexed | 2024-04-24T09:14:29Z |
| publishDate | 2021-01-01 |
| publisher | University of Zagreb. School of Dental Medicine |
| record_format | Article |
| series | Acta Stomatologica Croatica |
| spelling | doaj.art-10ff51e814e445ce8f2d8ae2bb7f53912024-04-15T17:11:26ZengUniversity of Zagreb. School of Dental MedicineActa Stomatologica Croatica0001-70191846-04102021-01-0155323824710.15644/asc55/3/1Comparison of Osteoimmunological and Microbiological Parameters of Extra Short and Longer Implants Loaded in the Posterior Mandible: A Split Mouth Randomized Clinical StudyBilge Karci0Elif Oncu1ı, Alanya Alaaddin Keykubat University, Faculty of Dentistry, Department of Periodontology, Alanya, Antalya, TurkeyNecmettin Erbakan University, Faculty of Dentistry, Department of Periodontology, Konya, TurkeyObjectives: This study aimed to evaluate the levels of TNF-α, PGE2, RANKL, RANK, OPG, the markers of periimplant bone loss in peri-implant crevicular fluid obtained around standard and extra short implants. Moreover, the levels of putative oral pathogens were investigated in the submucosal biofilm samples. Material and Methods: The implants were divided into two groups according to their lengths: standard (≥8 mm) and extra short (4 mm). A total of 60 implants were researched in 30 patients. The probing depth (PD), clinical attachment level (CAL), presence of bleeding on probing (BOP), 3-year survival rate (CSR), and bone loss (BL) were measured. Results: No statistically significant difference was found in the values of PD, CAL, BOP, CSR, and BL between the groups (P> 0.05). Total amounts of PGE2, TNF-α, RANKL, RANK, OPG, and RANKL/OPG were not statistically significantly different between the groups (P> 0.05). The abundance of F. nucleatum, T. forsythia, P. intermedia, P. gingivalis, S. oralis and T. denticola was compared between the groups and the results were not statistically significant (P> 0.05). Conclusion: The results of this study suggested that PGE2, TNF-α, RANKL, RANK, OPG, and RANKL/OPG in PICF, as well as microbiological parameters in submucosal biofilms, were similar between standard (≥8 mm) and extra short (4 mm) implants. Therefore, the implant length does not seem to influence the bone loss, levels of osteoimmunological and microbiological markers in the peri-implant tissues and survival rates.https://hrcak.srce.hr/file/381568MeSH terms: Dental ImplantationOsseointegrationBone-Implant InterfaceBiofilmsDental Implants |
| spellingShingle | Bilge Karci Elif Oncu Comparison of Osteoimmunological and Microbiological Parameters of Extra Short and Longer Implants Loaded in the Posterior Mandible: A Split Mouth Randomized Clinical Study Acta Stomatologica Croatica MeSH terms: Dental Implantation Osseointegration Bone-Implant Interface Biofilms Dental Implants |
| title | Comparison of Osteoimmunological and Microbiological Parameters of Extra Short and Longer Implants Loaded in the Posterior Mandible: A Split Mouth Randomized Clinical Study |
| title_full | Comparison of Osteoimmunological and Microbiological Parameters of Extra Short and Longer Implants Loaded in the Posterior Mandible: A Split Mouth Randomized Clinical Study |
| title_fullStr | Comparison of Osteoimmunological and Microbiological Parameters of Extra Short and Longer Implants Loaded in the Posterior Mandible: A Split Mouth Randomized Clinical Study |
| title_full_unstemmed | Comparison of Osteoimmunological and Microbiological Parameters of Extra Short and Longer Implants Loaded in the Posterior Mandible: A Split Mouth Randomized Clinical Study |
| title_short | Comparison of Osteoimmunological and Microbiological Parameters of Extra Short and Longer Implants Loaded in the Posterior Mandible: A Split Mouth Randomized Clinical Study |
| title_sort | comparison of osteoimmunological and microbiological parameters of extra short and longer implants loaded in the posterior mandible a split mouth randomized clinical study |
| topic | MeSH terms: Dental Implantation Osseointegration Bone-Implant Interface Biofilms Dental Implants |
| url | https://hrcak.srce.hr/file/381568 |
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