A Tertiary Care Hospital Experience During the COVID-19 Pandemic
Introduction: Early detection of the severity of COVID-19 disease is important for patient prognosis and effective use of hospital capacity. Early detection of critical patients and providing supportive treatment is the main goal of disease management. In this study, we evaluated demographic, clinic...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Bilimsel Tip Yayinevi
2021-06-01
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| Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| Subjects: | |
| Online Access: | http://floradergisi.org/managete/fu_folder/2021-02/257-266%20Mine%20Filiz.pdf |
| _version_ | 1797915643965603840 |
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| author | Mine Filiz Gülden Yılmaz Gonca Fidan Sümeyye Köşger Ekin Kadıoğlu Ümit Savaşçı Yavuz Çekli Nesrin Öcal Deniz Doğan Yakup Arslan Gürhan Taşkın Umut Kara Murat Kızılgün Levent Yamanel Cantürk Taşçı |
| author_facet | Mine Filiz Gülden Yılmaz Gonca Fidan Sümeyye Köşger Ekin Kadıoğlu Ümit Savaşçı Yavuz Çekli Nesrin Öcal Deniz Doğan Yakup Arslan Gürhan Taşkın Umut Kara Murat Kızılgün Levent Yamanel Cantürk Taşçı |
| author_sort | Mine Filiz |
| collection | DOAJ |
| description | Introduction: Early detection of the severity of COVID-19 disease is important for patient prognosis and effective use of hospital capacity. Early detection of critical patients and providing supportive treatment is the main goal of disease management. In this study, we evaluated demographic, clinical, laboratory and radiological findings in COVID-19 patients and aimed to find risk factors associated with poor prognosis.
Materials and Methods: A total of 579 cases hospitalized with the diagnosis of COVID-19 were evaluated retrospectively. The diagnosis of COVID-19 was confirmed by polymerase chain reaction (PCR) positivity or typical clinical, laboratory and radiological findings. The study population was divided into groups according to the World Health Organization (WHO) COVID-19 disease severity classification. Significant risk factors associated with severe disease and mortality were investigated by comparing the demographic, clinical, laboratory and radiological data of these groups.
Results: Mean age of the 579 cases was 54 ± 18.25, and 321 of them (55.4%) were male. Severe disease was detected in 131 (22.6%) patients and mortality rate was %8.29. The most common comorbidities were hypertension (31.8%), diabetes mellitus (18.5%) and coronary artery disease (17.8%), respectively. The most common symptoms at the time of admission to the hospital were cough (40.7%), fever (38°C; 33.6%) and shortness of breath (26.3%). Age, coronary artery disease and shortness of breath, neutrophil count, urea, CRP, ferritin, Pro-BNP, fibronogen, IL-6 values were found to be predictive variables for severe disease. Age, presence of shortness of breath, urea, ferritin and Pro-BNP values were found to be independent predictive variables for severe disease, and the cut-off points were calculated for these variables (age 59.5, urea 33.5 mg/dL, ferritin 50.8 µg/L and Pro-BNP 881 pg/mL).
Conclusion: Some predictive factors were demonstrated to detect severe disease in COVID-19 patients. It is important to predict poor prognosis based on these factors. It provides early detection of critical patients and it will be a guide for reducing mortality rates in these patients with effective treatment |
| first_indexed | 2024-04-10T12:45:56Z |
| format | Article |
| id | doaj.art-1100150104124287b8405e4f5465ceaf |
| institution | Directory Open Access Journal |
| issn | 1300-932X 1300-932X |
| language | English |
| last_indexed | 2024-04-10T12:45:56Z |
| publishDate | 2021-06-01 |
| publisher | Bilimsel Tip Yayinevi |
| record_format | Article |
| series | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| spelling | doaj.art-1100150104124287b8405e4f5465ceaf2023-02-15T16:14:04ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1300-932X2021-06-0126225726610.5578/flora.20219805A Tertiary Care Hospital Experience During the COVID-19 PandemicMine Filiz0https://orcid.org/0000-0002-6928-2435Gülden Yılmaz1https://orcid.org/0000-0002-2186-492XGonca Fidan2https://orcid.org/0000-0002-0972-4510Sümeyye Köşger3https://orcid.org/0000-0003-2838-8425Ekin Kadıoğlu4https://orcid.org/0000-0002-4870-1469Ümit Savaşçı5https://orcid.org/0000-0003-3663-2053Yavuz Çekli6https://orcid.org/0000-0002-0925-925XNesrin Öcal7https://orcid.org/0000-0002-3789-7769Deniz Doğan8https://orcid.org/0000-0003-2596-3113Yakup Arslan9https://orcid.org/0000-0002-9079-1701Gürhan Taşkın10https://orcid.org/0000-0002-6406-9221Umut Kara11https://orcid.org/0000-0001-5233-8255Murat Kızılgün12https://orcid.org/0000-0001-5551-4058Levent Yamanel13https://orcid.org/0000-0002-3704-3763Cantürk Taşçı14https://orcid.org/0000-0003-4596-5095Clinic of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Internal Diseases, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Chest Diseases, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Chest Diseases, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Chest Diseases, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Intensive Care, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Anesthesiology and Reanimation, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Medical Biochemistry, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Intensive Care, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyClinic of Chest Diseases, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, TurkeyIntroduction: Early detection of the severity of COVID-19 disease is important for patient prognosis and effective use of hospital capacity. Early detection of critical patients and providing supportive treatment is the main goal of disease management. In this study, we evaluated demographic, clinical, laboratory and radiological findings in COVID-19 patients and aimed to find risk factors associated with poor prognosis. Materials and Methods: A total of 579 cases hospitalized with the diagnosis of COVID-19 were evaluated retrospectively. The diagnosis of COVID-19 was confirmed by polymerase chain reaction (PCR) positivity or typical clinical, laboratory and radiological findings. The study population was divided into groups according to the World Health Organization (WHO) COVID-19 disease severity classification. Significant risk factors associated with severe disease and mortality were investigated by comparing the demographic, clinical, laboratory and radiological data of these groups. Results: Mean age of the 579 cases was 54 ± 18.25, and 321 of them (55.4%) were male. Severe disease was detected in 131 (22.6%) patients and mortality rate was %8.29. The most common comorbidities were hypertension (31.8%), diabetes mellitus (18.5%) and coronary artery disease (17.8%), respectively. The most common symptoms at the time of admission to the hospital were cough (40.7%), fever (38°C; 33.6%) and shortness of breath (26.3%). Age, coronary artery disease and shortness of breath, neutrophil count, urea, CRP, ferritin, Pro-BNP, fibronogen, IL-6 values were found to be predictive variables for severe disease. Age, presence of shortness of breath, urea, ferritin and Pro-BNP values were found to be independent predictive variables for severe disease, and the cut-off points were calculated for these variables (age 59.5, urea 33.5 mg/dL, ferritin 50.8 µg/L and Pro-BNP 881 pg/mL). Conclusion: Some predictive factors were demonstrated to detect severe disease in COVID-19 patients. It is important to predict poor prognosis based on these factors. It provides early detection of critical patients and it will be a guide for reducing mortality rates in these patients with effective treatmenthttp://floradergisi.org/managete/fu_folder/2021-02/257-266%20Mine%20Filiz.pdfcovid-19sars-cov-2pandemic |
| spellingShingle | Mine Filiz Gülden Yılmaz Gonca Fidan Sümeyye Köşger Ekin Kadıoğlu Ümit Savaşçı Yavuz Çekli Nesrin Öcal Deniz Doğan Yakup Arslan Gürhan Taşkın Umut Kara Murat Kızılgün Levent Yamanel Cantürk Taşçı A Tertiary Care Hospital Experience During the COVID-19 Pandemic Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi covid-19 sars-cov-2 pandemic |
| title | A Tertiary Care Hospital Experience During the COVID-19 Pandemic |
| title_full | A Tertiary Care Hospital Experience During the COVID-19 Pandemic |
| title_fullStr | A Tertiary Care Hospital Experience During the COVID-19 Pandemic |
| title_full_unstemmed | A Tertiary Care Hospital Experience During the COVID-19 Pandemic |
| title_short | A Tertiary Care Hospital Experience During the COVID-19 Pandemic |
| title_sort | tertiary care hospital experience during the covid 19 pandemic |
| topic | covid-19 sars-cov-2 pandemic |
| url | http://floradergisi.org/managete/fu_folder/2021-02/257-266%20Mine%20Filiz.pdf |
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