Association between office visit intervals and long‐term cardiovascular risk in hypertensive patients

Abstract Hypertension is a chronic disease that requires long‐term follow‐up in many patients, however, optimal visit intervals are not well‐established. This study aimed to evaluate the incidences of major cardiovascular events (MACEs) according to visit intervals. We analyzed data from 9894 hypert...

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Main Authors: Duon Kim, Hyunmook Jeong, Suhyun Kim, Ho‐Gyun Shin, Kyun‐Ik Park, Seung‐Pyo Lee, Hee‐Sun Lee, Ju‐Yeun Lee, Kwang‐il Kim, Si‐Hyuck Kang, Jang Hoon Lee, Se Yong Jang, Ju‐Hee Lee, Kye Hun Kim, Jae Yeong Cho, Jae‐Hyeong Park, Sue K. Park, Seungyeon Kim, Kwangsoo Kim, Hae‐Young Lee
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:The Journal of Clinical Hypertension
Subjects:
Online Access:https://doi.org/10.1111/jch.14698
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author Duon Kim
Hyunmook Jeong
Suhyun Kim
Ho‐Gyun Shin
Kyun‐Ik Park
Seung‐Pyo Lee
Hee‐Sun Lee
Ju‐Yeun Lee
Kwang‐il Kim
Si‐Hyuck Kang
Jang Hoon Lee
Se Yong Jang
Ju‐Hee Lee
Kye Hun Kim
Jae Yeong Cho
Jae‐Hyeong Park
Sue K. Park
Seungyeon Kim
Kwangsoo Kim
Hae‐Young Lee
author_facet Duon Kim
Hyunmook Jeong
Suhyun Kim
Ho‐Gyun Shin
Kyun‐Ik Park
Seung‐Pyo Lee
Hee‐Sun Lee
Ju‐Yeun Lee
Kwang‐il Kim
Si‐Hyuck Kang
Jang Hoon Lee
Se Yong Jang
Ju‐Hee Lee
Kye Hun Kim
Jae Yeong Cho
Jae‐Hyeong Park
Sue K. Park
Seungyeon Kim
Kwangsoo Kim
Hae‐Young Lee
author_sort Duon Kim
collection DOAJ
description Abstract Hypertension is a chronic disease that requires long‐term follow‐up in many patients, however, optimal visit intervals are not well‐established. This study aimed to evaluate the incidences of major cardiovascular events (MACEs) according to visit intervals. We analyzed data from 9894 hypertensive patients in the Korean Hypertension Cohort, which enrolled and followed up 11,043 patients for over 10 years. Participants were classified into five groups based on their median visit intervals (MVIs) during the 4‐year period and MACEs were compared among the groups. The patients were divided into clinically relevant MVIs of one (1013; 10%), two (1299; 13%), three (2732; 28%), four (2355; 24%), and six months (2515; 25%). The median follow‐up period was 5 years (range: 1745 ± 293 days). The longer visit interval groups did not have an increased cumulative incidence of MACE (12.9%, 11.8%, 6.7%, 5.9%, and 4%, respectively). In the Cox proportional hazards model, those in the longer MVI group had a smaller hazard ratio (HR) for MACEs or all‐cause death: 1.77 (95% confidence interval [CI], 1.45–2.17), 1.7 (95% CI: 1.41–2.05), 0.90 (95% CI: 0.74–1.09) and 0.64 (95% CI: 0.52–0.79), respectively (Reference MVI group of 75–104 days). In conclusion, a follow‐up visits with a longer interval of 3–6 months was not associated with an increased risk of MACE or all‐cause death in hypertensive patients. Therefore, once medication adjustment is stabilized, a longer interval of 3–6 months is reasonable, reducing medical expenses without increasing the risk of cardiovascular outcomes.
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spelling doaj.art-110628b0dcdf414d9eae6f65d8978c2e2023-10-30T13:25:57ZengWileyThe Journal of Clinical Hypertension1524-61751751-71762023-08-0125874875610.1111/jch.14698Association between office visit intervals and long‐term cardiovascular risk in hypertensive patientsDuon Kim0Hyunmook Jeong1Suhyun Kim2Ho‐Gyun Shin3Kyun‐Ik Park4Seung‐Pyo Lee5Hee‐Sun Lee6Ju‐Yeun Lee7Kwang‐il Kim8Si‐Hyuck Kang9Jang Hoon Lee10Se Yong Jang11Ju‐Hee Lee12Kye Hun Kim13Jae Yeong Cho14Jae‐Hyeong Park15Sue K. Park16Seungyeon Kim17Kwangsoo Kim18Hae‐Young Lee19Department of Medicine Seoul National University College of Medicine SeoulSouth KoreaBiomedical Research Institute Seoul National University Hospital SeoulSouth KoreaTransdisciplinary Department of Medicine & Advanced Technology Seoul National University Hospital SeoulSouth KoreaNational Evidence‐based Healthcare Collaborating Agency (NECA) SeoulSouth KoreaNational Evidence‐based Healthcare Collaborating Agency (NECA) SeoulSouth KoreaDepartment of Internal Medicine Seoul National University Hospital SeoulSouth KoreaDepartment of Internal Medicine Seoul National University Hospital SeoulSouth KoreaCollege of Pharmacy Seoul National University SeoulSouth KoreaDepartment of Internal Medicine Seoul National University Bundang Hospital SungnamSouth KoreaDepartment of Internal Medicine Seoul National University Bundang Hospital SungnamSouth KoreaDepartment of Internal Medicine Kyungpook National University Hospital, School of Medicine Kyungpook National University DaeguSouth KoreaDepartment of Internal Medicine Kyungpook National University Hospital, School of Medicine Kyungpook National University DaeguSouth KoreaDivision of Cardiology Department of Internal Medicine Chungbuk National University Hospital Chungbuk National University College of Medicine CheongjuSouth KoreaDepartment of Cardiovascular Medicine Chonnam National University Medical School/Hospital GwangjuSouth KoreaDepartment of Cardiovascular Medicine Chonnam National University Medical School/Hospital GwangjuSouth KoreaDepartment of Internal Medicine Chungnam National University College of Medicine DaejeonSouth KoreaDepartment of Preventive Medicine Seoul National University College of Medicine SeoulSouth KoreaCollege of Pharmacy Dankook University CheonanSouth KoreaTransdisciplinary Department of Medicine & Advanced Technology Seoul National University Hospital SeoulSouth KoreaDepartment of Internal Medicine Seoul National University Hospital SeoulSouth KoreaAbstract Hypertension is a chronic disease that requires long‐term follow‐up in many patients, however, optimal visit intervals are not well‐established. This study aimed to evaluate the incidences of major cardiovascular events (MACEs) according to visit intervals. We analyzed data from 9894 hypertensive patients in the Korean Hypertension Cohort, which enrolled and followed up 11,043 patients for over 10 years. Participants were classified into five groups based on their median visit intervals (MVIs) during the 4‐year period and MACEs were compared among the groups. The patients were divided into clinically relevant MVIs of one (1013; 10%), two (1299; 13%), three (2732; 28%), four (2355; 24%), and six months (2515; 25%). The median follow‐up period was 5 years (range: 1745 ± 293 days). The longer visit interval groups did not have an increased cumulative incidence of MACE (12.9%, 11.8%, 6.7%, 5.9%, and 4%, respectively). In the Cox proportional hazards model, those in the longer MVI group had a smaller hazard ratio (HR) for MACEs or all‐cause death: 1.77 (95% confidence interval [CI], 1.45–2.17), 1.7 (95% CI: 1.41–2.05), 0.90 (95% CI: 0.74–1.09) and 0.64 (95% CI: 0.52–0.79), respectively (Reference MVI group of 75–104 days). In conclusion, a follow‐up visits with a longer interval of 3–6 months was not associated with an increased risk of MACE or all‐cause death in hypertensive patients. Therefore, once medication adjustment is stabilized, a longer interval of 3–6 months is reasonable, reducing medical expenses without increasing the risk of cardiovascular outcomes.https://doi.org/10.1111/jch.14698cardiovascular eventhypertensionvisit intervals
spellingShingle Duon Kim
Hyunmook Jeong
Suhyun Kim
Ho‐Gyun Shin
Kyun‐Ik Park
Seung‐Pyo Lee
Hee‐Sun Lee
Ju‐Yeun Lee
Kwang‐il Kim
Si‐Hyuck Kang
Jang Hoon Lee
Se Yong Jang
Ju‐Hee Lee
Kye Hun Kim
Jae Yeong Cho
Jae‐Hyeong Park
Sue K. Park
Seungyeon Kim
Kwangsoo Kim
Hae‐Young Lee
Association between office visit intervals and long‐term cardiovascular risk in hypertensive patients
The Journal of Clinical Hypertension
cardiovascular event
hypertension
visit intervals
title Association between office visit intervals and long‐term cardiovascular risk in hypertensive patients
title_full Association between office visit intervals and long‐term cardiovascular risk in hypertensive patients
title_fullStr Association between office visit intervals and long‐term cardiovascular risk in hypertensive patients
title_full_unstemmed Association between office visit intervals and long‐term cardiovascular risk in hypertensive patients
title_short Association between office visit intervals and long‐term cardiovascular risk in hypertensive patients
title_sort association between office visit intervals and long term cardiovascular risk in hypertensive patients
topic cardiovascular event
hypertension
visit intervals
url https://doi.org/10.1111/jch.14698
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