Engineering Electrospun Nanofibers for the Treatment of Oral Diseases
With the increase of consumption of high-sugar foods, beverages, tobacco, and alcohol, the incidence rate of oral diseases has been increasing year by year. Statistics showed that the prevalence of oral diseases such as dental caries, dental pulpal disease, and periodontal disease has reached as hig...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-12-01
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| Series: | Frontiers in Chemistry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2021.797523/full |
| _version_ | 1828920235279777792 |
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| author | Yuanfei Wang Yingnan Liu Xiaopei Zhang Xiaopei Zhang Na Liu Na Liu Xixi Yu Meihua Gao Wanchun Wang Tong Wu Tong Wu Tong Wu |
| author_facet | Yuanfei Wang Yingnan Liu Xiaopei Zhang Xiaopei Zhang Na Liu Na Liu Xixi Yu Meihua Gao Wanchun Wang Tong Wu Tong Wu Tong Wu |
| author_sort | Yuanfei Wang |
| collection | DOAJ |
| description | With the increase of consumption of high-sugar foods, beverages, tobacco, and alcohol, the incidence rate of oral diseases has been increasing year by year. Statistics showed that the prevalence of oral diseases such as dental caries, dental pulpal disease, and periodontal disease has reached as high as 97% in 2015 in China. It is thus urgent to develop functional materials or products for the treatment of oral diseases. Electrospinning has been a widely used technology that is capable of utilizing polymer solution to generate micro/nano fibers under an appropriate high voltage condition. Owing to their excellent structures and biological performances, materials prepared by electrospinning technology have been used for a wide range of oral-related applications, such as tissue restoration, controlled drug release, anti-cancer, etc. In this regard, this article reviews the application and progress of electrospun nanofibers to various oral diseases in recent years. Firstly, engineering strategies of a variety of nanofiber structures together with their resultant functions will be introduced. Then, biological functions of electrospun nanofibers as well as their applications in the treatment of oral diseases are summarized and demonstrated. Finally, the development viewpoint of functional nanofibers is prospected, which is expected to lay the foundation and propose the direction for further clinical application. |
| first_indexed | 2024-12-13T21:42:39Z |
| format | Article |
| id | doaj.art-1108e12c73184576bb0f4d68d3e67b44 |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-12-13T21:42:39Z |
| publishDate | 2021-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-1108e12c73184576bb0f4d68d3e67b442022-12-21T23:30:30ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462021-12-01910.3389/fchem.2021.797523797523Engineering Electrospun Nanofibers for the Treatment of Oral DiseasesYuanfei Wang0Yingnan Liu1Xiaopei Zhang2Xiaopei Zhang3Na Liu4Na Liu5Xixi Yu6Meihua Gao7Wanchun Wang8Tong Wu9Tong Wu10Tong Wu11Qingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, ChinaInstitute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, ChinaInstitute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, ChinaQingdao Medical College, Qingdao University, Qingdao, ChinaInstitute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, ChinaQingdao Medical College, Qingdao University, Qingdao, ChinaQingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, ChinaQingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, ChinaQingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, ChinaInstitute of Neuroregeneration and Neurorehabilitation, Qingdao University, Qingdao, ChinaQingdao Medical College, Qingdao University, Qingdao, ChinaDepartment of Cosmetic and Plastic Surgery, Affiliated Hospital of Qingdao University, Qingdao, ChinaWith the increase of consumption of high-sugar foods, beverages, tobacco, and alcohol, the incidence rate of oral diseases has been increasing year by year. Statistics showed that the prevalence of oral diseases such as dental caries, dental pulpal disease, and periodontal disease has reached as high as 97% in 2015 in China. It is thus urgent to develop functional materials or products for the treatment of oral diseases. Electrospinning has been a widely used technology that is capable of utilizing polymer solution to generate micro/nano fibers under an appropriate high voltage condition. Owing to their excellent structures and biological performances, materials prepared by electrospinning technology have been used for a wide range of oral-related applications, such as tissue restoration, controlled drug release, anti-cancer, etc. In this regard, this article reviews the application and progress of electrospun nanofibers to various oral diseases in recent years. Firstly, engineering strategies of a variety of nanofiber structures together with their resultant functions will be introduced. Then, biological functions of electrospun nanofibers as well as their applications in the treatment of oral diseases are summarized and demonstrated. Finally, the development viewpoint of functional nanofibers is prospected, which is expected to lay the foundation and propose the direction for further clinical application.https://www.frontiersin.org/articles/10.3389/fchem.2021.797523/fullelectrospun nanofibersstructuresbiofunctionsoral diseasestranslational application |
| spellingShingle | Yuanfei Wang Yingnan Liu Xiaopei Zhang Xiaopei Zhang Na Liu Na Liu Xixi Yu Meihua Gao Wanchun Wang Tong Wu Tong Wu Tong Wu Engineering Electrospun Nanofibers for the Treatment of Oral Diseases Frontiers in Chemistry electrospun nanofibers structures biofunctions oral diseases translational application |
| title | Engineering Electrospun Nanofibers for the Treatment of Oral Diseases |
| title_full | Engineering Electrospun Nanofibers for the Treatment of Oral Diseases |
| title_fullStr | Engineering Electrospun Nanofibers for the Treatment of Oral Diseases |
| title_full_unstemmed | Engineering Electrospun Nanofibers for the Treatment of Oral Diseases |
| title_short | Engineering Electrospun Nanofibers for the Treatment of Oral Diseases |
| title_sort | engineering electrospun nanofibers for the treatment of oral diseases |
| topic | electrospun nanofibers structures biofunctions oral diseases translational application |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2021.797523/full |
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