Diagnosis and treatment of destructive forms of acute pancreatitis
Purpose of the study. The study of the diagnosis and treatment of destructive forms of acute pancreatitis and the identification of possible ways to optimize them. Materials and methods. Destructive forms of acute pancreatitis were found in 16,8%. The algorithm for treating acute destructive panc...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine
2019-06-01
|
| Series: | Сучасні медичні технології |
| Subjects: | |
| Online Access: | https://zmapo-journal.com/index.php/journal/article/view/168 |
| _version_ | 1811343856535339008 |
|---|---|
| author | V. V. Mishchenko V. V. Hrubnyk P. I. Pustovoyt V. V. Horyachyy V. V. Velychko R. Yu. Vododyuk |
| author_facet | V. V. Mishchenko V. V. Hrubnyk P. I. Pustovoyt V. V. Horyachyy V. V. Velychko R. Yu. Vododyuk |
| author_sort | V. V. Mishchenko |
| collection | DOAJ |
| description | Purpose of the study. The study of the diagnosis and treatment of destructive forms of acute pancreatitis and the identification of possible ways to optimize them.
Materials and methods. Destructive forms of acute pancreatitis were found in 16,8%. The algorithm for treating acute destructive pancreatitis consisted in artificial ventilation of the lungs, adequate infusion therapy, peridural anesthesia, setting up a nasoenteric probe, stimulating the bowels, correcting hemodynamics, intraand extracorporal detoxification, antisecretory, anti-bacterial, hepatoprotective, cerebroprotective, antioxidant therapy, directed immune correction, use of anti-enzyme drugs, suppression of the release of mediators inflammation, external secretory activity of the pancreas. Medical video laparoscopy and puncture interventions under the control of ultrasound were used as the first stage of surgical treatment. The indications for traditional surgical interventions are large areas of aseptic destruction, unlimited infected pancreatic necrosis, infection of necrotic areas with complete cell sequestration, abscesses with large sequesters, abdominal phlegmon, signs of progressive multiple organ failure and the development of arousal hemorrhage, perforation of cystic formations in the abdominal cavity, perforation of a hollow organ, purulent peritonitis.
Results. The developed therapeutic tactics allowed, in destructive forms of acute pancreatitis, to achieve a reduction in overall mortality to 23,4%.
Conclusion. Diagnostic and treatment tactics for destructive forms of acute pancreatitis should be standardized depending on the timing, severity of the disease, localization and prevalence of the destructive process, systemic and local complications. |
| first_indexed | 2024-04-13T19:36:13Z |
| format | Article |
| id | doaj.art-1109290896e64e4c971b3f224e7c7381 |
| institution | Directory Open Access Journal |
| issn | 2072-9367 |
| language | English |
| last_indexed | 2024-04-13T19:36:13Z |
| publishDate | 2019-06-01 |
| publisher | Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine |
| record_format | Article |
| series | Сучасні медичні технології |
| spelling | doaj.art-1109290896e64e4c971b3f224e7c73812022-12-22T02:33:00ZengZaporizhia Medical Academy of Post-Graduate Education Ministry of Health of UkraineСучасні медичні технології2072-93672019-06-012(41)657010.34287/MMT.2(41).2019.13168Diagnosis and treatment of destructive forms of acute pancreatitisV. V. Mishchenko0V. V. Hrubnyk1P. I. Pustovoyt2V. V. Horyachyy3V. V. Velychko4R. Yu. Vododyuk5Odessa National Medical University, Department of Surgery № 1 Odessa, UkraineOdessa National Medical University, Department of Surgery № 1 Odessa, UkraineOdessa Regional Clinical Hospital Odessa, UkraineOdessa Region State Administration Odessa, UkraineOdessa Regional Clinical Hospital Odessa, UkraineOdessa Regional Clinical Hospital Odessa, UkrainePurpose of the study. The study of the diagnosis and treatment of destructive forms of acute pancreatitis and the identification of possible ways to optimize them. Materials and methods. Destructive forms of acute pancreatitis were found in 16,8%. The algorithm for treating acute destructive pancreatitis consisted in artificial ventilation of the lungs, adequate infusion therapy, peridural anesthesia, setting up a nasoenteric probe, stimulating the bowels, correcting hemodynamics, intraand extracorporal detoxification, antisecretory, anti-bacterial, hepatoprotective, cerebroprotective, antioxidant therapy, directed immune correction, use of anti-enzyme drugs, suppression of the release of mediators inflammation, external secretory activity of the pancreas. Medical video laparoscopy and puncture interventions under the control of ultrasound were used as the first stage of surgical treatment. The indications for traditional surgical interventions are large areas of aseptic destruction, unlimited infected pancreatic necrosis, infection of necrotic areas with complete cell sequestration, abscesses with large sequesters, abdominal phlegmon, signs of progressive multiple organ failure and the development of arousal hemorrhage, perforation of cystic formations in the abdominal cavity, perforation of a hollow organ, purulent peritonitis. Results. The developed therapeutic tactics allowed, in destructive forms of acute pancreatitis, to achieve a reduction in overall mortality to 23,4%. Conclusion. Diagnostic and treatment tactics for destructive forms of acute pancreatitis should be standardized depending on the timing, severity of the disease, localization and prevalence of the destructive process, systemic and local complications.https://zmapo-journal.com/index.php/journal/article/view/168acute, destructive, pancreatitisdiagnosistreatment |
| spellingShingle | V. V. Mishchenko V. V. Hrubnyk P. I. Pustovoyt V. V. Horyachyy V. V. Velychko R. Yu. Vododyuk Diagnosis and treatment of destructive forms of acute pancreatitis Сучасні медичні технології acute, destructive, pancreatitis diagnosis treatment |
| title | Diagnosis and treatment of destructive forms of acute pancreatitis |
| title_full | Diagnosis and treatment of destructive forms of acute pancreatitis |
| title_fullStr | Diagnosis and treatment of destructive forms of acute pancreatitis |
| title_full_unstemmed | Diagnosis and treatment of destructive forms of acute pancreatitis |
| title_short | Diagnosis and treatment of destructive forms of acute pancreatitis |
| title_sort | diagnosis and treatment of destructive forms of acute pancreatitis |
| topic | acute, destructive, pancreatitis diagnosis treatment |
| url | https://zmapo-journal.com/index.php/journal/article/view/168 |
| work_keys_str_mv | AT vvmishchenko diagnosisandtreatmentofdestructiveformsofacutepancreatitis AT vvhrubnyk diagnosisandtreatmentofdestructiveformsofacutepancreatitis AT pipustovoyt diagnosisandtreatmentofdestructiveformsofacutepancreatitis AT vvhoryachyy diagnosisandtreatmentofdestructiveformsofacutepancreatitis AT vvvelychko diagnosisandtreatmentofdestructiveformsofacutepancreatitis AT ryuvododyuk diagnosisandtreatmentofdestructiveformsofacutepancreatitis |