Double Alkynylation of Quinoline-5,8-diones and their <i>In-silico</i> and Antimicrobial Studies

A double alkynylation of quinoline-5,8-dione to furnished bis-alkynylquinoline-5,8-dione in good yields and their in silico and antimicrobial studies is described. This was achieved by cross-coupling of 6,7- dibromoquinoline-5,8-dione with various terminal alkynes in the presence of bis(triphenylph...

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Bibliographic Details
Main Authors: MA Ezeokonkwo, JA Ezugwu, SN Okafor, EA Onoabedje, EU Godwin-Nwakwasi, FN Ibeanu
Format: Article
Language:English
Published: Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP) 2018-08-01
Series:Journal of Applied Sciences and Environmental Management
Subjects:
Online Access:https://www.ajol.info/index.php/jasem/article/view/175634