Effects of Prenatal Exposure to Titanium Dioxide Nanoparticles on DNA Methylation and Gene Expression Profile in the Mouse Brain

Effects of Prenatal Exposure to Titanium Dioxide Nanoparticles on DNA Methylation and Gene Expression Profile in the Mouse Brain

Background and Objectives: Titanium dioxide nanoparticles (TiO2-NP) are important materials used in commercial practice. Reportedly, TiO2-NP exposure during pregnancy can affect the development of the central nervous system in mouse offspring; however, the underlying mechanism remains unknown. In th...

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Bibliographic Details
Main Authors: Ken Tachibana, Shotaro Kawazoe, Atsuto Onoda, Masakazu Umezawa, Ken Takeda
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Toxicology
Subjects:
brain
DNA methylation
gene expression
titanium dioxide nanoparticle
prenatal exposure
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2021.705910/full

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