Effect of MSCs and MSC-Derived Extracellular Vesicles on Human Blood Coagulation

Effect of MSCs and MSC-Derived Extracellular Vesicles on Human Blood Coagulation

Mesenchymal stem cells (MSCs) have emerged as a potent therapeutic tool for the treatment of a number of pathologies, including immune pathologies. However, unwelcome effects of MSCs on blood coagulation have been reported, motivating us to explore the thrombotic properties of human MSCs from the um...

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Bibliographic Details
Main Authors: Denis N. Silachev, Kirill V. Goryunov, Margarita A. Shpilyuk, Olga S. Beznoschenko, Natalya Y. Morozova, Elizaveta E. Kraevaya, Vasily A. Popkov, Irina B. Pevzner, Ljubava D. Zorova, Ekaterina A. Evtushenko, Natalia L. Starodubtseva, Alexey S. Kononikhin, Anna E. Bugrova, Evgeniy G. Evtushenko, Egor Y. Plotnikov, Dmitry B. Zorov, Gennady T. Sukhikh
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
mesenchymal stem cells
extracellular vesicles
thrombosis
heparin
procoagulant proteins
Online Access:http://www.mdpi.com/2073-4409/8/3/258

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