Low-molecular weight heparin increases circulating sFlt-1 levels and enhances urinary elimination.

Low-molecular weight heparin increases circulating sFlt-1 levels and enhances urinary elimination.

RATIONALE: Preeclampsia is a devastating medical complication of pregnancy which leads to maternal and fetal morbidity and mortality. While the etiology of preeclampsia is unclear, human and animal studies suggest that excessive circulating levels of soluble fms-like tyrosine-kinase-1 (sFlt-1), an a...

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Main Authors: Henning Hagmann, Verena Bossung, Abdel Ali Belaidi, Alexander Fridman, S Ananth Karumanchi, Ravi Thadhani, Bernhard Schermer, Peter Mallmann, Guenter Schwarz, Thomas Benzing, Paul T Brinkkoetter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3897409?pdf=render

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