Surface Layer Protein A Expressed in <i>Clostridioides difficile</i> DJNS06-36 Possesses an Encephalitogenic Mimotope of Myelin Basic Protein

Surface Layer Protein A Expressed in <i>Clostridioides difficile</i> DJNS06-36 Possesses an Encephalitogenic Mimotope of Myelin Basic Protein

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Recent studies suggest that migration of Th1 and Th17 cells specific for enteric bacteria from the gut to the CNS may lead to the initiation and/or exacerbation of autoimmune diseases including MS....

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Bibliographic Details
Main Authors: John E. Mindur, Sudhir K. Yadav, Naoko Ito, Mitsutoshi Senoh, Haru Kato, Suhayl Dhib-Jalbut, Kouichi Ito
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Microorganisms
Subjects:
<i>Clostridioides difficile</i>
surface layer protein A
multiple sclerosis
myelin basic protein
mimotope
Online Access:https://www.mdpi.com/2076-2607/9/1/34

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