Invasive pneumococcal disease: From a tertiary care hospital in the post-vaccine era

A breakthrough infection occurring with 13-valent pneumococcal conjugate vaccine (PCV13) in Turkey are previously described. A breakthrough infection is defined as IPD in a child who had received ≥ 1 PCV-7 or PCV-13 and for which the pneumococcal isolate was a vaccine serotype. During one year perio...

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Bibliographic Details
Main Authors: Sevgen Tanır Basaranoglu, Eda Karadag Oncel, Kubra Aykac, Yasemin Ozsurekci, Ali Bülent Cengiz, Ates Kara, Mehmet Ceyhan
Format: Article
Language:English
Published: Taylor & Francis Group 2017-04-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2016.1256519
Description
Summary:A breakthrough infection occurring with 13-valent pneumococcal conjugate vaccine (PCV13) in Turkey are previously described. A breakthrough infection is defined as IPD in a child who had received ≥ 1 PCV-7 or PCV-13 and for which the pneumococcal isolate was a vaccine serotype. During one year period, among 6 patients with invasive pneumococcal infection, 2 patients were considered to have a vaccine failure with serotype 19F. Antibiotic resistance results were remarkable; macrolide resistance were observed in all strains except one, and high and intermediate penicillin resistance were determined in 2 strains.
ISSN:2164-5515
2164-554X