Invasive pneumococcal disease: From a tertiary care hospital in the post-vaccine era

A breakthrough infection occurring with 13-valent pneumococcal conjugate vaccine (PCV13) in Turkey are previously described. A breakthrough infection is defined as IPD in a child who had received ≥ 1 PCV-7 or PCV-13 and for which the pneumococcal isolate was a vaccine serotype. During one year perio...

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Main Authors: Sevgen Tanır Basaranoglu, Eda Karadag Oncel, Kubra Aykac, Yasemin Ozsurekci, Ali Bülent Cengiz, Ates Kara, Mehmet Ceyhan
Format: Article
Language:English
Published: Taylor & Francis Group 2017-04-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2016.1256519
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author Sevgen Tanır Basaranoglu
Eda Karadag Oncel
Kubra Aykac
Yasemin Ozsurekci
Ali Bülent Cengiz
Ates Kara
Mehmet Ceyhan
author_facet Sevgen Tanır Basaranoglu
Eda Karadag Oncel
Kubra Aykac
Yasemin Ozsurekci
Ali Bülent Cengiz
Ates Kara
Mehmet Ceyhan
author_sort Sevgen Tanır Basaranoglu
collection DOAJ
description A breakthrough infection occurring with 13-valent pneumococcal conjugate vaccine (PCV13) in Turkey are previously described. A breakthrough infection is defined as IPD in a child who had received ≥ 1 PCV-7 or PCV-13 and for which the pneumococcal isolate was a vaccine serotype. During one year period, among 6 patients with invasive pneumococcal infection, 2 patients were considered to have a vaccine failure with serotype 19F. Antibiotic resistance results were remarkable; macrolide resistance were observed in all strains except one, and high and intermediate penicillin resistance were determined in 2 strains.
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spelling doaj.art-111b30ea0dbf494b8e9c1fc36cf4ecc82023-09-25T11:00:55ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2017-04-0113496296410.1080/21645515.2016.12565191256519Invasive pneumococcal disease: From a tertiary care hospital in the post-vaccine eraSevgen Tanır Basaranoglu0Eda Karadag Oncel1Kubra Aykac2Yasemin Ozsurekci3Ali Bülent Cengiz4Ates Kara5Mehmet Ceyhan6Hacettepe University Faculty of MedicineHacettepe University Faculty of MedicineHacettepe University Faculty of MedicineHacettepe University Faculty of MedicineHacettepe University Faculty of MedicineHacettepe University Faculty of MedicineHacettepe University Faculty of MedicineA breakthrough infection occurring with 13-valent pneumococcal conjugate vaccine (PCV13) in Turkey are previously described. A breakthrough infection is defined as IPD in a child who had received ≥ 1 PCV-7 or PCV-13 and for which the pneumococcal isolate was a vaccine serotype. During one year period, among 6 patients with invasive pneumococcal infection, 2 patients were considered to have a vaccine failure with serotype 19F. Antibiotic resistance results were remarkable; macrolide resistance were observed in all strains except one, and high and intermediate penicillin resistance were determined in 2 strains.http://dx.doi.org/10.1080/21645515.2016.1256519antibiotic resistancebreakthrough infectioninvasive pneumococcus diseasesurveillancestreptococcus pneumoniaevaccinationvaccine failure
spellingShingle Sevgen Tanır Basaranoglu
Eda Karadag Oncel
Kubra Aykac
Yasemin Ozsurekci
Ali Bülent Cengiz
Ates Kara
Mehmet Ceyhan
Invasive pneumococcal disease: From a tertiary care hospital in the post-vaccine era
Human Vaccines & Immunotherapeutics
antibiotic resistance
breakthrough infection
invasive pneumococcus disease
surveillance
streptococcus pneumoniae
vaccination
vaccine failure
title Invasive pneumococcal disease: From a tertiary care hospital in the post-vaccine era
title_full Invasive pneumococcal disease: From a tertiary care hospital in the post-vaccine era
title_fullStr Invasive pneumococcal disease: From a tertiary care hospital in the post-vaccine era
title_full_unstemmed Invasive pneumococcal disease: From a tertiary care hospital in the post-vaccine era
title_short Invasive pneumococcal disease: From a tertiary care hospital in the post-vaccine era
title_sort invasive pneumococcal disease from a tertiary care hospital in the post vaccine era
topic antibiotic resistance
breakthrough infection
invasive pneumococcus disease
surveillance
streptococcus pneumoniae
vaccination
vaccine failure
url http://dx.doi.org/10.1080/21645515.2016.1256519
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