The impact of vestibular function on cognitive–motor interference: a case–control study on dual-tasking in persons with bilateral vestibulopathy and normal hearing
Abstract Bilateral vestibulopathy (BV) is a chronic vestibular disorder, characterized by bilaterally absent or significantly impaired vestibular function. Symptoms typically include, but are not limited to, unsteadiness and movement-induced blurred vision (oscillopsia). This prospective case–contro...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-08-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-40465-2 |
| _version_ | 1797452559283126272 |
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| author | Maya Danneels Ruth Van Hecke Laura Leyssens Raymond van de Berg Ingeborg Dhooge Dirk Cambier Stefan Delrue Vincent Van Rompaey Leen Maes |
| author_facet | Maya Danneels Ruth Van Hecke Laura Leyssens Raymond van de Berg Ingeborg Dhooge Dirk Cambier Stefan Delrue Vincent Van Rompaey Leen Maes |
| author_sort | Maya Danneels |
| collection | DOAJ |
| description | Abstract Bilateral vestibulopathy (BV) is a chronic vestibular disorder, characterized by bilaterally absent or significantly impaired vestibular function. Symptoms typically include, but are not limited to, unsteadiness and movement-induced blurred vision (oscillopsia). This prospective case–control study aimed to elucidate the impact of BV on cognitive and motor performance and on cognitive–motor interference. Cognitive and motor performance, as well as cognitive–motor interference were measured in persons with BV and normal hearing using the 2BALANCE dual-task protocol. The experimental group was matched to a healthy control group based on age, sex, and educational level. The 2BALANCE protocol comprises cognitive tests assessing visuospatial memory, mental rotation, visual and auditory response inhibition, visual and auditory working memory, and processing speed. The cognitive tests were performed in single-task condition (while seated), and in dual-task condition (during a static and a dynamic motor task). The static motor task consisted of balancing on a force platform with foam pad. The dynamic motor task consisted of walking at a self-selected speed. These motor tasks were also performed in single-task condition. A generalized estimating equations model was used to investigate group differences for all cognitive and motor outcome measures. The estimated marginal means, as well as the odds ratios (OR), and their 95% confidence intervals (CI) were calculated. For the backward digit recall test, a baseline measurement was performed and analyzed using a student-t test. A total of 22 patients with BV and normal hearing and 22 healthy control subjects were assessed [mean age (SD), BV = 53.66 (13.35) and HC = 53.21 (13.35), 68% male]. The BV group had poorer mental rotation skills in single-task condition, compared to the control group [odds ratio (OR) = 2.30, confidence interval (CI) = 1.12–4.73, P = 0.024]. Similarly, auditory and visual working memory were also poorer in the BV group in single-task condition (P = 0.028 and P = 0.003, respectively). The BV group also performed poorer on the mental rotation task and the visual response inhibition task in dual-task condition (OR = 2.96, CI = 1.57–5.59, P < 0.001 and OR = 1.08, CI = 1.01–1.16, P = 0.032, respectively). Additionally, an interaction effect, indicating increased cognitive–motor interference in the BV group, was observed for mental rotation, response inhibition, and auditory working memory (P = 0.003 to 0.028). All static motor outcome parameters indicated more postural sway in the BV group compared to the control group for all test conditions (P < 0.001 to 0.026). No group differences were noted for the dynamic motor task. These findings suggest a link between vestibular function and cognitive performance, as well as a greater interference between cognitive and motor performance in BV, compared to healthy controls. |
| first_indexed | 2024-03-09T15:10:26Z |
| format | Article |
| id | doaj.art-111c7211f9924785a068a24633514883 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-09T15:10:26Z |
| publishDate | 2023-08-01 |
| publisher | Nature Portfolio |
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| spelling | doaj.art-111c7211f9924785a068a246335148832023-11-26T13:22:10ZengNature PortfolioScientific Reports2045-23222023-08-0113111210.1038/s41598-023-40465-2The impact of vestibular function on cognitive–motor interference: a case–control study on dual-tasking in persons with bilateral vestibulopathy and normal hearingMaya Danneels0Ruth Van Hecke1Laura Leyssens2Raymond van de Berg3Ingeborg Dhooge4Dirk Cambier5Stefan Delrue6Vincent Van Rompaey7Leen Maes8Department of Rehabilitation Sciences, Ghent UniversityDepartment of Rehabilitation Sciences, Ghent UniversityDepartment of Rehabilitation Sciences, Ghent UniversityDepartment of Otorhinolaryngology and Head and Neck Surgery, Maastricht University Medical CenterDepartment of Otorhinolaryngology, Ghent University HospitalDepartment of Rehabilitation Sciences, Ghent UniversityDepartment of Otorhinolaryngology and Head and Neck Surgery, Sint Lucas HospitalDepartment of Otorhinolaryngology and Head and Neck Surgery, Antwerp University HospitalDepartment of Rehabilitation Sciences, Ghent UniversityAbstract Bilateral vestibulopathy (BV) is a chronic vestibular disorder, characterized by bilaterally absent or significantly impaired vestibular function. Symptoms typically include, but are not limited to, unsteadiness and movement-induced blurred vision (oscillopsia). This prospective case–control study aimed to elucidate the impact of BV on cognitive and motor performance and on cognitive–motor interference. Cognitive and motor performance, as well as cognitive–motor interference were measured in persons with BV and normal hearing using the 2BALANCE dual-task protocol. The experimental group was matched to a healthy control group based on age, sex, and educational level. The 2BALANCE protocol comprises cognitive tests assessing visuospatial memory, mental rotation, visual and auditory response inhibition, visual and auditory working memory, and processing speed. The cognitive tests were performed in single-task condition (while seated), and in dual-task condition (during a static and a dynamic motor task). The static motor task consisted of balancing on a force platform with foam pad. The dynamic motor task consisted of walking at a self-selected speed. These motor tasks were also performed in single-task condition. A generalized estimating equations model was used to investigate group differences for all cognitive and motor outcome measures. The estimated marginal means, as well as the odds ratios (OR), and their 95% confidence intervals (CI) were calculated. For the backward digit recall test, a baseline measurement was performed and analyzed using a student-t test. A total of 22 patients with BV and normal hearing and 22 healthy control subjects were assessed [mean age (SD), BV = 53.66 (13.35) and HC = 53.21 (13.35), 68% male]. The BV group had poorer mental rotation skills in single-task condition, compared to the control group [odds ratio (OR) = 2.30, confidence interval (CI) = 1.12–4.73, P = 0.024]. Similarly, auditory and visual working memory were also poorer in the BV group in single-task condition (P = 0.028 and P = 0.003, respectively). The BV group also performed poorer on the mental rotation task and the visual response inhibition task in dual-task condition (OR = 2.96, CI = 1.57–5.59, P < 0.001 and OR = 1.08, CI = 1.01–1.16, P = 0.032, respectively). Additionally, an interaction effect, indicating increased cognitive–motor interference in the BV group, was observed for mental rotation, response inhibition, and auditory working memory (P = 0.003 to 0.028). All static motor outcome parameters indicated more postural sway in the BV group compared to the control group for all test conditions (P < 0.001 to 0.026). No group differences were noted for the dynamic motor task. These findings suggest a link between vestibular function and cognitive performance, as well as a greater interference between cognitive and motor performance in BV, compared to healthy controls.https://doi.org/10.1038/s41598-023-40465-2 |
| spellingShingle | Maya Danneels Ruth Van Hecke Laura Leyssens Raymond van de Berg Ingeborg Dhooge Dirk Cambier Stefan Delrue Vincent Van Rompaey Leen Maes The impact of vestibular function on cognitive–motor interference: a case–control study on dual-tasking in persons with bilateral vestibulopathy and normal hearing Scientific Reports |
| title | The impact of vestibular function on cognitive–motor interference: a case–control study on dual-tasking in persons with bilateral vestibulopathy and normal hearing |
| title_full | The impact of vestibular function on cognitive–motor interference: a case–control study on dual-tasking in persons with bilateral vestibulopathy and normal hearing |
| title_fullStr | The impact of vestibular function on cognitive–motor interference: a case–control study on dual-tasking in persons with bilateral vestibulopathy and normal hearing |
| title_full_unstemmed | The impact of vestibular function on cognitive–motor interference: a case–control study on dual-tasking in persons with bilateral vestibulopathy and normal hearing |
| title_short | The impact of vestibular function on cognitive–motor interference: a case–control study on dual-tasking in persons with bilateral vestibulopathy and normal hearing |
| title_sort | impact of vestibular function on cognitive motor interference a case control study on dual tasking in persons with bilateral vestibulopathy and normal hearing |
| url | https://doi.org/10.1038/s41598-023-40465-2 |
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