An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol
For detection of cannabidiol (CBD)—an important ingredient in <i>Cannabis sativa</i> L.—amino magnetic nanoparticle-decorated graphene (Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub>-GN) was prepared in the form of nanocomposites, and then modified on a gl...
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MDPI AG
2021-08-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/11/9/2227 |
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| author | Yi Zhang Zongyi You Chunsheng Hou Liangliang Liu Aiping Xiao |
| author_facet | Yi Zhang Zongyi You Chunsheng Hou Liangliang Liu Aiping Xiao |
| author_sort | Yi Zhang |
| collection | DOAJ |
| description | For detection of cannabidiol (CBD)—an important ingredient in <i>Cannabis sativa</i> L.—amino magnetic nanoparticle-decorated graphene (Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub>-GN) was prepared in the form of nanocomposites, and then modified on a glassy carbon electrode (GCE), resulting in a novel electrochemical sensor (Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub>-GN/GCE). The applied Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub> nanoparticles and GN exhibited typical structures and intended surface groups through characterizations via transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray powder diffraction (XRD), vibrating sample magnetometer (VSM), and Raman spectroscopy. The Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub>-GN/GCE showed the maximum electrochemical signal for CBD during the comparison of fabricated components via the cyclic voltammetry method, and was systematically investigated in the composition and treatment of components, pH, scan rate, and quantitative analysis ability. Under optimal conditions, the Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub>-GN/GCE exhibited a good detection limit (0.04 μmol L<sup>−1</sup>) with a linear range of 0.1 μmol L<sup>−1</sup> to 100 μmol L<sup>−1</sup> (<i>r</i><sup>2</sup> = 0.984). In the detection of CBD in the extract of <i>C. sativa</i> leaves, the results of the electrochemical method using the Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub>-GN/GCE were in good agreement with those of the HPLC method. Based on these findings, the proposed sensor could be further developed for the portable and rapid detection of natural active compounds in the food, agricultural, and pharmaceutical fields. |
| first_indexed | 2024-03-10T07:22:52Z |
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| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-10T07:22:52Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
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| series | Nanomaterials |
| spelling | doaj.art-111e063a134147eba49aa489c0c79dae2023-11-22T14:29:16ZengMDPI AGNanomaterials2079-49912021-08-01119222710.3390/nano11092227An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of CannabidiolYi Zhang0Zongyi You1Chunsheng Hou2Liangliang Liu3Aiping Xiao4Institute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaFor detection of cannabidiol (CBD)—an important ingredient in <i>Cannabis sativa</i> L.—amino magnetic nanoparticle-decorated graphene (Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub>-GN) was prepared in the form of nanocomposites, and then modified on a glassy carbon electrode (GCE), resulting in a novel electrochemical sensor (Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub>-GN/GCE). The applied Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub> nanoparticles and GN exhibited typical structures and intended surface groups through characterizations via transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray powder diffraction (XRD), vibrating sample magnetometer (VSM), and Raman spectroscopy. The Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub>-GN/GCE showed the maximum electrochemical signal for CBD during the comparison of fabricated components via the cyclic voltammetry method, and was systematically investigated in the composition and treatment of components, pH, scan rate, and quantitative analysis ability. Under optimal conditions, the Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub>-GN/GCE exhibited a good detection limit (0.04 μmol L<sup>−1</sup>) with a linear range of 0.1 μmol L<sup>−1</sup> to 100 μmol L<sup>−1</sup> (<i>r</i><sup>2</sup> = 0.984). In the detection of CBD in the extract of <i>C. sativa</i> leaves, the results of the electrochemical method using the Fe<sub>3</sub>O<sub>4</sub>-NH<sub>2</sub>-GN/GCE were in good agreement with those of the HPLC method. Based on these findings, the proposed sensor could be further developed for the portable and rapid detection of natural active compounds in the food, agricultural, and pharmaceutical fields.https://www.mdpi.com/2079-4991/11/9/2227cannabidiol<i>Cannabis sativa</i> L.electrochemical sensorgraphenemagnetic nanoparticles |
| spellingShingle | Yi Zhang Zongyi You Chunsheng Hou Liangliang Liu Aiping Xiao An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol Nanomaterials cannabidiol <i>Cannabis sativa</i> L. electrochemical sensor graphene magnetic nanoparticles |
| title | An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol |
| title_full | An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol |
| title_fullStr | An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol |
| title_full_unstemmed | An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol |
| title_short | An Electrochemical Sensor Based on Amino Magnetic Nanoparticle-Decorated Graphene for Detection of Cannabidiol |
| title_sort | electrochemical sensor based on amino magnetic nanoparticle decorated graphene for detection of cannabidiol |
| topic | cannabidiol <i>Cannabis sativa</i> L. electrochemical sensor graphene magnetic nanoparticles |
| url | https://www.mdpi.com/2079-4991/11/9/2227 |
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