Association of Pretreatment Hippocampal Volume With Neurocognitive Function in Patients Treated With Hippocampal Avoidance Whole Brain Radiation Therapy for Brain Metastases: Secondary Analysis of NRG Oncology/RTOG 0933

Association of Pretreatment Hippocampal Volume With Neurocognitive Function in Patients Treated With Hippocampal Avoidance Whole Brain Radiation Therapy for Brain Metastases: Secondary Analysis of NRG Oncology/RTOG 0933

Purpose: Hippocampal volume (HV) is an established predicting factor for neurocognitive function (NCF) in neurodegenerative disease. Whether the same phenomenon exists with hippocampal-avoidant whole brain radiation therapy is not known; therefore, we assessed the association of baseline HV with NCF...

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Main Authors: Christopher D. Abraham, MD, Stephanie L. Pugh, PhD, Joseph A. Bovi, MD, Vinai Gondi, MD, Minesh P. Mehta, MD, Tammie Benzinger, MD, Christopher J. Owen, MS, Simon S. Lo, MD, Vijayananda Kundapur, MD, Paul D. Brown, MD, Alexander Y. Sun, MD, Steven P. Howard, MD, Albert S. DeNittis, MD, Clifford G. Robinson, MD, Lisa A. Kachnic, MD
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109421002177

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