Single-sex schistosomiasis: a mini review
Schistosomiasis is a neglected tropical disease caused by dioecious blood flukes of the genus Schistosoma and second to malaria as a parasitic disease with significant socio-economic impacts. Mating is essential for maturation of male and female schistosomes and for females to lay of eggs, which are...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1158805/full |
| _version_ | 1827964598009987072 |
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| author | Haoran Zhong Haoran Zhong Yamei Jin Yamei Jin |
| author_facet | Haoran Zhong Haoran Zhong Yamei Jin Yamei Jin |
| author_sort | Haoran Zhong |
| collection | DOAJ |
| description | Schistosomiasis is a neglected tropical disease caused by dioecious blood flukes of the genus Schistosoma and second to malaria as a parasitic disease with significant socio-economic impacts. Mating is essential for maturation of male and female schistosomes and for females to lay of eggs, which are responsible for the pathogenesis and propagation of the life cycle beyond the mammalian host. Single-sex schistosomes, which do not produce viable eggs without mating, have been overlooked given the symptomatic paucity of the single-sex schistosomiasis and limited diagnostic toolkit. Besides, single-sex schistosomes are less sensitive to praziquantel. Therefore, these issues should be considered to achieve the elimination of this infection disease. The aim of this review is to summarize current progress in research of single-sex schistosomes and host-parasite interactions. |
| first_indexed | 2024-04-09T17:19:03Z |
| format | Article |
| id | doaj.art-1122ebe5c0e64295b3d98128e1214257 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-04-09T17:19:03Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-1122ebe5c0e64295b3d98128e12142572023-04-19T04:59:37ZengFrontiers Media S.A.Frontiers in Immunology1664-32242023-04-011410.3389/fimmu.2023.11588051158805Single-sex schistosomiasis: a mini reviewHaoran Zhong0Haoran Zhong1Yamei Jin2Yamei Jin3National Reference Laboratory for Animal Schistosomiasis, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, ChinaKey Laboratory of Animal Parasitology of Ministry of Agriculture and Rural Affairs, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, ChinaNational Reference Laboratory for Animal Schistosomiasis, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, ChinaKey Laboratory of Animal Parasitology of Ministry of Agriculture and Rural Affairs, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, ChinaSchistosomiasis is a neglected tropical disease caused by dioecious blood flukes of the genus Schistosoma and second to malaria as a parasitic disease with significant socio-economic impacts. Mating is essential for maturation of male and female schistosomes and for females to lay of eggs, which are responsible for the pathogenesis and propagation of the life cycle beyond the mammalian host. Single-sex schistosomes, which do not produce viable eggs without mating, have been overlooked given the symptomatic paucity of the single-sex schistosomiasis and limited diagnostic toolkit. Besides, single-sex schistosomes are less sensitive to praziquantel. Therefore, these issues should be considered to achieve the elimination of this infection disease. The aim of this review is to summarize current progress in research of single-sex schistosomes and host-parasite interactions.https://www.frontiersin.org/articles/10.3389/fimmu.2023.1158805/fullschistosomesingle-sex infectionomicshost-parasite interactionimmune regulation |
| spellingShingle | Haoran Zhong Haoran Zhong Yamei Jin Yamei Jin Single-sex schistosomiasis: a mini review Frontiers in Immunology schistosome single-sex infection omics host-parasite interaction immune regulation |
| title | Single-sex schistosomiasis: a mini review |
| title_full | Single-sex schistosomiasis: a mini review |
| title_fullStr | Single-sex schistosomiasis: a mini review |
| title_full_unstemmed | Single-sex schistosomiasis: a mini review |
| title_short | Single-sex schistosomiasis: a mini review |
| title_sort | single sex schistosomiasis a mini review |
| topic | schistosome single-sex infection omics host-parasite interaction immune regulation |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1158805/full |
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