Delirium in the intensive care unit

Delirium is not only a mental change but also a complex clinical syndrome with multiple pathophysiological changes. Delirium is an acute brain dysfunction accompanied by change or fluctuation of basal mental status, loss of attention with disorganized thinking, or altered level of consciousness. Alt...

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Main Authors: Ratković Sanja, Rajković Marija, Hadžibegović Adi, Jovanović Nemanja, Dimić Nemanja, Stanisavljević Jovana
Format: Article
Language:English
Published: Serbian Society of Anesthesiologists and Intensivists 2021-01-01
Series:Serbian Journal of Anesthesia and Intensive Therapy
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/2217-7744/2021/2217-77442103061R.pdf
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author Ratković Sanja
Rajković Marija
Hadžibegović Adi
Jovanović Nemanja
Dimić Nemanja
Stanisavljević Jovana
author_facet Ratković Sanja
Rajković Marija
Hadžibegović Adi
Jovanović Nemanja
Dimić Nemanja
Stanisavljević Jovana
author_sort Ratković Sanja
collection DOAJ
description Delirium is not only a mental change but also a complex clinical syndrome with multiple pathophysiological changes. Delirium is an acute brain dysfunction accompanied by change or fluctuation of basal mental status, loss of attention with disorganized thinking, or altered level of consciousness. Although healthcare professionals realize the importance of recognizing delirium, it frequently goes unrecognized in the intensive care unit. Acute delirium is associated with increased mortality, morbidity, length of stay, and healthcare costs in intensive care units and hospitals. The consequences of delirium are long-term cognitive impairment, functional disability, post-discharge cognitive dysfunction, and institutionalization. Critical illness-related delirium can affect the diagnosis and treatment of primary diseases and disappears with the improvement of primary diseases. In the intensive care unit, delirium has been reported in 40% to 60% of non-ventilated patients and up to 50% to 80% of critically ill patients undergoing mechanical ventilation. Recent investigations have shown that delirium is preventable in 30-40% of cases. Available sedation and delirium monitoring instruments allow clinicians to recognize these forms of brain dysfunction. Multiple management strategies such as ABCDE, eCASH, and ESCAPE are helpful to prevent and treat delirium and improve the prognosis of critically ill patients.
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spelling doaj.art-11233b19fc5a411696f4de28cfecbf512022-12-21T18:19:47ZengSerbian Society of Anesthesiologists and IntensivistsSerbian Journal of Anesthesia and Intensive Therapy2466-488X2021-01-01433-4617210.5937/sjait2104061R2217-77442103061RDelirium in the intensive care unitRatković Sanja0Rajković Marija1Hadžibegović Adi2https://orcid.org/0000-0003-4956-3093Jovanović Nemanja3Dimić Nemanja4Stanisavljević Jovana5Klinički centar Srbije, Centar za anesteziologiju i reanimatologiju, Beograd, SerbiaKlinički centar Srbije, Centar za anesteziologiju i reanimatologiju, Beograd, SerbiaKlinički centar Srbije, Centar za anesteziologiju i reanimatologiju, Beograd, SerbiaKlinički centar Srbije, Klinika za neurohirurgiju, Beograd, SerbiaKliničko bolnički centar "Dr Dragiša Mišović - Dedinje", Beograd, SerbiaKlinički centar Srbije, Centar za anesteziologiju i reanimatologiju, Beograd, SerbiaDelirium is not only a mental change but also a complex clinical syndrome with multiple pathophysiological changes. Delirium is an acute brain dysfunction accompanied by change or fluctuation of basal mental status, loss of attention with disorganized thinking, or altered level of consciousness. Although healthcare professionals realize the importance of recognizing delirium, it frequently goes unrecognized in the intensive care unit. Acute delirium is associated with increased mortality, morbidity, length of stay, and healthcare costs in intensive care units and hospitals. The consequences of delirium are long-term cognitive impairment, functional disability, post-discharge cognitive dysfunction, and institutionalization. Critical illness-related delirium can affect the diagnosis and treatment of primary diseases and disappears with the improvement of primary diseases. In the intensive care unit, delirium has been reported in 40% to 60% of non-ventilated patients and up to 50% to 80% of critically ill patients undergoing mechanical ventilation. Recent investigations have shown that delirium is preventable in 30-40% of cases. Available sedation and delirium monitoring instruments allow clinicians to recognize these forms of brain dysfunction. Multiple management strategies such as ABCDE, eCASH, and ESCAPE are helpful to prevent and treat delirium and improve the prognosis of critically ill patients.https://scindeks-clanci.ceon.rs/data/pdf/2217-7744/2021/2217-77442103061R.pdfdeliriumcritical carediagnosismanagementrisk factors
spellingShingle Ratković Sanja
Rajković Marija
Hadžibegović Adi
Jovanović Nemanja
Dimić Nemanja
Stanisavljević Jovana
Delirium in the intensive care unit
Serbian Journal of Anesthesia and Intensive Therapy
delirium
critical care
diagnosis
management
risk factors
title Delirium in the intensive care unit
title_full Delirium in the intensive care unit
title_fullStr Delirium in the intensive care unit
title_full_unstemmed Delirium in the intensive care unit
title_short Delirium in the intensive care unit
title_sort delirium in the intensive care unit
topic delirium
critical care
diagnosis
management
risk factors
url https://scindeks-clanci.ceon.rs/data/pdf/2217-7744/2021/2217-77442103061R.pdf
work_keys_str_mv AT ratkovicsanja deliriumintheintensivecareunit
AT rajkovicmarija deliriumintheintensivecareunit
AT hadzibegovicadi deliriumintheintensivecareunit
AT jovanovicnemanja deliriumintheintensivecareunit
AT dimicnemanja deliriumintheintensivecareunit
AT stanisavljevicjovana deliriumintheintensivecareunit