Cardiac Valve Granulocytic Sarcoma Infiltration as an Complicating Acute Myelogenous Leukemia: a Case Report

Granulocytic sarcomas (chloromas) are rare extramedullary tumors consisting of primitive granulocytic cells. We report here on a case of a 23-year-old man who presented with a generalized swelling. He is known case of acute myelomonocytic leukemia. Granulocytic sarcomas are rare, destructive, extram...

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Main Authors: Mehrdad Payandeh, Mehrnoush Aeinfar, Ali Maleki, Mohammad Erfan Zare
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2012-03-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/325
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author Mehrdad Payandeh
Mehrnoush Aeinfar
Ali Maleki
Mohammad Erfan Zare
author_facet Mehrdad Payandeh
Mehrnoush Aeinfar
Ali Maleki
Mohammad Erfan Zare
author_sort Mehrdad Payandeh
collection DOAJ
description Granulocytic sarcomas (chloromas) are rare extramedullary tumors consisting of primitive granulocytic cells. We report here on a case of a 23-year-old man who presented with a generalized swelling. He is known case of acute myelomonocytic leukemia. Granulocytic sarcomas are rare, destructive, extramedullary tumor masses that consist of immature granulocytic cells. In this unusual patient's case, the location and invasive nature of the tumor be important that can die the patient if we cannot treat patient urgently. Optimal therapy for these patients has not been well defined: standard AML chemotherapy is moderately effective and should be considered for all suitable cases.To reduce the risk of subsequent ANLL in patients with nonleukemic GS, it is important that accurate histologic diagnosis is established initially for GS and that all isolated cases of GS, even those that appear to be cured by resection or irradiation of the tumor, are treated with intensive chemotherapy similar to that used to treat ANLL dur ng the nonleukemic period as soon as possible.
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spelling doaj.art-11248b248f84439eb6deb7bbce86b0af2023-09-02T07:32:39ZengTehran University of Medical SciencesInternational Journal of Hematology-Oncology and Stem Cell Research2008-22072012-03-0161Cardiac Valve Granulocytic Sarcoma Infiltration as an Complicating Acute Myelogenous Leukemia: a Case ReportMehrdad Payandeh0Mehrnoush Aeinfar1Ali Maleki2Mohammad Erfan Zare3Department of hematology, Kermanshah University of Medical Science, Kermanshah, IranDepartment of hematology, Kermanshah University of Medical Science, Kermanshah, IranHematology center , Kermanshah university of medical science, IranMedical Biology Research Center, Kermanshah University of Medical Science, Kermanshah, IranGranulocytic sarcomas (chloromas) are rare extramedullary tumors consisting of primitive granulocytic cells. We report here on a case of a 23-year-old man who presented with a generalized swelling. He is known case of acute myelomonocytic leukemia. Granulocytic sarcomas are rare, destructive, extramedullary tumor masses that consist of immature granulocytic cells. In this unusual patient's case, the location and invasive nature of the tumor be important that can die the patient if we cannot treat patient urgently. Optimal therapy for these patients has not been well defined: standard AML chemotherapy is moderately effective and should be considered for all suitable cases.To reduce the risk of subsequent ANLL in patients with nonleukemic GS, it is important that accurate histologic diagnosis is established initially for GS and that all isolated cases of GS, even those that appear to be cured by resection or irradiation of the tumor, are treated with intensive chemotherapy similar to that used to treat ANLL dur ng the nonleukemic period as soon as possible.https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/325AMLCardiac valveChloroma
spellingShingle Mehrdad Payandeh
Mehrnoush Aeinfar
Ali Maleki
Mohammad Erfan Zare
Cardiac Valve Granulocytic Sarcoma Infiltration as an Complicating Acute Myelogenous Leukemia: a Case Report
International Journal of Hematology-Oncology and Stem Cell Research
AML
Cardiac valve
Chloroma
title Cardiac Valve Granulocytic Sarcoma Infiltration as an Complicating Acute Myelogenous Leukemia: a Case Report
title_full Cardiac Valve Granulocytic Sarcoma Infiltration as an Complicating Acute Myelogenous Leukemia: a Case Report
title_fullStr Cardiac Valve Granulocytic Sarcoma Infiltration as an Complicating Acute Myelogenous Leukemia: a Case Report
title_full_unstemmed Cardiac Valve Granulocytic Sarcoma Infiltration as an Complicating Acute Myelogenous Leukemia: a Case Report
title_short Cardiac Valve Granulocytic Sarcoma Infiltration as an Complicating Acute Myelogenous Leukemia: a Case Report
title_sort cardiac valve granulocytic sarcoma infiltration as an complicating acute myelogenous leukemia a case report
topic AML
Cardiac valve
Chloroma
url https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/325
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AT mehrnoushaeinfar cardiacvalvegranulocyticsarcomainfiltrationasancomplicatingacutemyelogenousleukemiaacasereport
AT alimaleki cardiacvalvegranulocyticsarcomainfiltrationasancomplicatingacutemyelogenousleukemiaacasereport
AT mohammaderfanzare cardiacvalvegranulocyticsarcomainfiltrationasancomplicatingacutemyelogenousleukemiaacasereport