Altered Retrograde Signaling Patterns in Breast Cancer Cells Cybrids with H and J Mitochondrial DNA Haplogroups

Altered Retrograde Signaling Patterns in Breast Cancer Cells Cybrids with H and J Mitochondrial DNA Haplogroups

The aim of this study was to determine the role of retrograde signaling (mitochondria to nucleus) in MCF7 breast cancer cells. Therefore, in the present study, MCF7-H and MCF7-J cybrids were produced using the mitochondria from the same H and J individuals that were already used in our non-diseased...

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Bibliographic Details
Main Authors: Steven Chang, Lata Singh, Kunal Thaker, Sina Abedi, Mithalesh K. Singh, Tej H. Patel, Marilyn Chwa, Shari R. Atilano, Nitin Udar, Daniela Bota, Maria Cristina Kenney
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
cybrids
mitochondria
cGAS-STING pathway
Online Access:https://www.mdpi.com/1422-0067/23/12/6687

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