Caspase-1: A Promising Target for Preserving Blood–Brain Barrier Integrity in Acute Stroke

Caspase-1: A Promising Target for Preserving Blood–Brain Barrier Integrity in Acute Stroke

The blood–brain barrier (BBB) acts as a physical and biochemical barrier that plays a fundamental role in regulating the blood-to-brain influx of endogenous and exogenous components and maintaining the homeostatic microenvironment of the central nervous system (CNS). Acute stroke leads to BBB disrup...

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Bibliographic Details
Main Authors: Xiaodong Ye, Guini Song, Shanshan Huang, Qiming Liang, Yongkang Fang, Lifei Lian, Suiqiang Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
caspase-1
ischemic stroke
hemorrhagic stroke
blood-brain barrier
pyroptosis
cerebral edema
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.856372/full

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