Increased Tumor Intrinsic Growth Potential and Decreased Immune Function Orchestrate the Progression of Lung Adenocarcinoma

Increased Tumor Intrinsic Growth Potential and Decreased Immune Function Orchestrate the Progression of Lung Adenocarcinoma

BackgroundThe overall 5-year survival of lung cancer was reported to be only ~15%, with lung adenocarcinoma (LUAD) as the main pathological subtype. Before developing into invasive stages, LUAD undergoes pre-invasive stages of adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma (MIA),...

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Bibliographic Details
Main Authors: Yue Zhao, Jun Shang, Jian Gao, Han Han, Zhendong Gao, Yueren Yan, Qiang Zheng, Ting Ye, Fangqiu Fu, Chaoqiang Deng, Zelin Ma, Yang Zhang, Difan Zheng, Shanbo Zheng, Yuan Li, Zhiwei Cao, Leming Shi, Haiquan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
imbalance
tumor intrinsic growth potential
immune response
progression
lung adenocarcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.921761/full

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