Emerging Next-Generation Target for Cancer Immunotherapy Research: The Orphan Nuclear Receptor NR2F6

Emerging Next-Generation Target for Cancer Immunotherapy Research: The Orphan Nuclear Receptor NR2F6

Additional therapeutic targets suitable for boosting anti-tumor effector responses have been found inside effector CD4<sup>+</sup> and CD8<sup>+</sup> T cells. It is likely that future treatment options will combine surface receptor and intracellular protein targets. Utilizin...

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Bibliographic Details
Main Authors:	Victoria Klepsch, Kerstin Siegmund, Gottfried Baier
Format:	Article
Language:	English
Published:	MDPI AG 2021-05-01
Series:	Cancers
Subjects:	tumor immunology orphan nuclear receptor NR2F6 tumor-promoting function alternative and druggable cancer immune checkpoint transcriptional repressor of CD4<sup>+</sup> and CD8<sup>+</sup> effector but not regulatory T cell functions NR2F6 inhibition as first-in-class cancer immunotherapy concept
Online Access:	https://www.mdpi.com/2072-6694/13/11/2600

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