Risk factors for mortality in fournier's gangrene in a general hospital: use of simplified founier gangrene severe index score (SFGSI)
ABSTRACT Objective To evaluate risk factors for mortality in patients with Fournier's gangrene (FG), with emphasis in the Simplified Fournier Gangrene Severe Index Score (SFGSI). Materials and Methods This was a cross-sectional study that was carried out from January 2010 to December 2014, wi...
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Sociedade Brasileira de Urologia
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| Series: | International Brazilian Journal of Urology |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382018000100095&lng=en&tlng=en |
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| author | Carlos Eugênio Lira Tenório Salvador Vilar Correia Lima Amanda Vasconcelos de Albuquerque Mariana Pauferro Cavalcanti Flávio Teles |
| author_facet | Carlos Eugênio Lira Tenório Salvador Vilar Correia Lima Amanda Vasconcelos de Albuquerque Mariana Pauferro Cavalcanti Flávio Teles |
| author_sort | Carlos Eugênio Lira Tenório |
| collection | DOAJ |
| description | ABSTRACT Objective To evaluate risk factors for mortality in patients with Fournier's gangrene (FG), with emphasis in the Simplified Fournier Gangrene Severe Index Score (SFGSI). Materials and Methods This was a cross-sectional study that was carried out from January 2010 to December 2014, with 124 patients treated for FG in a General Hospital. Several clinical and laboratory variables, including SFGSI, were evaluated and correlated with mortality through univariate analysis and logistic regression. Results Of the 124 patients, 99 were men (79.8%), the mean age was 50.8±19.5 years and the main comorbidity was diabetes mellitus (51.6%). The mortality rate was 25.8%. Variables that presented independent correlation with mortality were the extension of the lesion to the abdomen (OR=4.0, CI=1.10-14.68, p=0.03), hematocrit (OR=0.81, CI=0.73-0.90, p<0.0001), potassium (OR=2.41, CI=1.13-5.10, p=0.02) and creatinine (OR=2.15, CI= 1.04-4.41, p=0.03). When hematocrit, potassium and creatinine were tested together, as part of the SFGSI, a >2 result was the largest of the independent predictors of mortality (OR=50.2; CI=13.18-191.47; p<0.0001). Conclusion The SFGSI >2 presented a higher correlation with mortality than any variable tested alone. It seems to be a promising alternative to evaluate predictors of mortality in Fournier's gangrene. The main advantage is easy applicability because it contains only three parameters and can be used immediately after patient's admission. |
| first_indexed | 2024-12-19T20:29:50Z |
| format | Article |
| id | doaj.art-112a567c1e684a67bc6b7bda54372bb0 |
| institution | Directory Open Access Journal |
| issn | 1677-6119 |
| language | English |
| last_indexed | 2024-12-19T20:29:50Z |
| publisher | Sociedade Brasileira de Urologia |
| record_format | Article |
| series | International Brazilian Journal of Urology |
| spelling | doaj.art-112a567c1e684a67bc6b7bda54372bb02022-12-21T20:06:43ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-61194419510110.1590/s1677-5538.ibju.2017.0193S1677-55382018000100095Risk factors for mortality in fournier's gangrene in a general hospital: use of simplified founier gangrene severe index score (SFGSI)Carlos Eugênio Lira TenórioSalvador Vilar Correia LimaAmanda Vasconcelos de AlbuquerqueMariana Pauferro CavalcantiFlávio TelesABSTRACT Objective To evaluate risk factors for mortality in patients with Fournier's gangrene (FG), with emphasis in the Simplified Fournier Gangrene Severe Index Score (SFGSI). Materials and Methods This was a cross-sectional study that was carried out from January 2010 to December 2014, with 124 patients treated for FG in a General Hospital. Several clinical and laboratory variables, including SFGSI, were evaluated and correlated with mortality through univariate analysis and logistic regression. Results Of the 124 patients, 99 were men (79.8%), the mean age was 50.8±19.5 years and the main comorbidity was diabetes mellitus (51.6%). The mortality rate was 25.8%. Variables that presented independent correlation with mortality were the extension of the lesion to the abdomen (OR=4.0, CI=1.10-14.68, p=0.03), hematocrit (OR=0.81, CI=0.73-0.90, p<0.0001), potassium (OR=2.41, CI=1.13-5.10, p=0.02) and creatinine (OR=2.15, CI= 1.04-4.41, p=0.03). When hematocrit, potassium and creatinine were tested together, as part of the SFGSI, a >2 result was the largest of the independent predictors of mortality (OR=50.2; CI=13.18-191.47; p<0.0001). Conclusion The SFGSI >2 presented a higher correlation with mortality than any variable tested alone. It seems to be a promising alternative to evaluate predictors of mortality in Fournier's gangrene. The main advantage is easy applicability because it contains only three parameters and can be used immediately after patient's admission.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382018000100095&lng=en&tlng=enFournier GangreneRisk FactorsMortalityFasciitisNecrotizing |
| spellingShingle | Carlos Eugênio Lira Tenório Salvador Vilar Correia Lima Amanda Vasconcelos de Albuquerque Mariana Pauferro Cavalcanti Flávio Teles Risk factors for mortality in fournier's gangrene in a general hospital: use of simplified founier gangrene severe index score (SFGSI) International Brazilian Journal of Urology Fournier Gangrene Risk Factors Mortality Fasciitis Necrotizing |
| title | Risk factors for mortality in fournier's gangrene in a general hospital: use of simplified founier gangrene severe index score (SFGSI) |
| title_full | Risk factors for mortality in fournier's gangrene in a general hospital: use of simplified founier gangrene severe index score (SFGSI) |
| title_fullStr | Risk factors for mortality in fournier's gangrene in a general hospital: use of simplified founier gangrene severe index score (SFGSI) |
| title_full_unstemmed | Risk factors for mortality in fournier's gangrene in a general hospital: use of simplified founier gangrene severe index score (SFGSI) |
| title_short | Risk factors for mortality in fournier's gangrene in a general hospital: use of simplified founier gangrene severe index score (SFGSI) |
| title_sort | risk factors for mortality in fournier s gangrene in a general hospital use of simplified founier gangrene severe index score sfgsi |
| topic | Fournier Gangrene Risk Factors Mortality Fasciitis Necrotizing |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382018000100095&lng=en&tlng=en |
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