An Inducible Cre-<i>lox</i> System to Analyze the Role of LLO in <i>Listeria monocytogenes</i> Pathogenesis

An Inducible Cre-<i>lox</i> System to Analyze the Role of LLO in <i>Listeria monocytogenes</i> Pathogenesis

Listeriolysin O (LLO) is a pore-forming cytolysin that allows <i>Listeria monocytogenes</i> to escape from phagocytic vacuoles and enter the host cell cytosol. LLO is expressed continuously during infection, but it has been a challenge to evaluate the importance of LLO secreted in the ho...

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Bibliographic Details
Main Authors: Brittney N. Nguyen, Daniel A. Portnoy
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Toxins
Subjects:
pathogenesis
cytotoxicity
pore-forming toxin
cholesterol-dependent cytolysin
vaccine
Online Access:https://www.mdpi.com/2072-6651/12/1/38

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