Evaluation of qSOFA and variation of hematochemical profile in cats naturally infected with feline panleukopenia virus
Feline panleukopenia (FP) is a fatal viral disease that predisposes cats to sepsis and organ failure. Owing to a wide variety of clinical findings, hematochemical examinations are significant for the determination of early signs of disease-related complications. The aim of this study is to investiga...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2023-03-01
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| Series: | Open Veterinary Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/ovs-2022-0118 |
| _version_ | 1797848621187596288 |
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| author | Gülersoy Erdem Erol Büşra Burcu Ok Mahmut Sevinç Mutlu |
| author_facet | Gülersoy Erdem Erol Büşra Burcu Ok Mahmut Sevinç Mutlu |
| author_sort | Gülersoy Erdem |
| collection | DOAJ |
| description | Feline panleukopenia (FP) is a fatal viral disease that predisposes cats to sepsis and organ failure. Owing to a wide variety of clinical findings, hematochemical examinations are significant for the determination of early signs of disease-related complications. The aim of this study is to investigate the diagnostic efficacy of certain hematochemical parameters together with quick Sepsis-related Organ Failure Assessment (qSOFA) in cats with FP. A total of 10 healthy and 30 panleukopenic cats were included in this study. Physical examinations revealed that the body temperature was highest in septic panleukopenic cats (p < 0.009) and they had higher qSOFA scores (p = 0.000). Hemogram analysis revealed that leukocyte, lymphocyte, granulocyte, erythrocyte, and hemoglobin levels were lower in non-septic panleukopenic cats compared with the healthy ones (p < 0.030). Also, monocyte and mean corpuscular hemoglobin levels were lower in septic ones (p < 0.048). Serum biochemistry profiling revealed higher blood urea nitrogen, creatinine, alanine aminotransferase, lactate dehydrogenase, total bilirubin, and C-reactive protein levels in panleukopenic cats (p < 0.033). As a result, it was concluded that although the qSOFA is not sufficient to distinguish sepsis in cats, unlike dogs, in order to achieve a positive clinical outcome, when evaluated together with hematochemical variables, it may help in making early diagnosis of FP-related complications. |
| first_indexed | 2024-04-09T18:30:29Z |
| format | Article |
| id | doaj.art-112d2f673ccd43d9bfe5ca77677802ba |
| institution | Directory Open Access Journal |
| issn | 2544-8951 |
| language | English |
| last_indexed | 2024-04-09T18:30:29Z |
| publishDate | 2023-03-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Veterinary Science |
| spelling | doaj.art-112d2f673ccd43d9bfe5ca77677802ba2023-04-11T17:07:19ZengDe GruyterOpen Veterinary Science2544-89512023-03-014198637610.1515/ovs-2022-0118Evaluation of qSOFA and variation of hematochemical profile in cats naturally infected with feline panleukopenia virusGülersoy Erdem0Erol Büşra Burcu1Ok Mahmut2Sevinç Mutlu3Department of Internal Medicine, Faculty of Veterinary Medicine, Harran University, 63000, Şanlıurfa, TurkeyDepartment of Internal Medicine, Faculty of Veterinary Medicine, Selçuk University, 42250, Konya, TurkeyDepartment of Internal Medicine, Faculty of Veterinary Medicine, Selçuk University, 42250, Konya, TurkeyDepartment of Internal Medicine, Faculty of Veterinary Medicine, Selçuk University, 42250, Konya, TurkeyFeline panleukopenia (FP) is a fatal viral disease that predisposes cats to sepsis and organ failure. Owing to a wide variety of clinical findings, hematochemical examinations are significant for the determination of early signs of disease-related complications. The aim of this study is to investigate the diagnostic efficacy of certain hematochemical parameters together with quick Sepsis-related Organ Failure Assessment (qSOFA) in cats with FP. A total of 10 healthy and 30 panleukopenic cats were included in this study. Physical examinations revealed that the body temperature was highest in septic panleukopenic cats (p < 0.009) and they had higher qSOFA scores (p = 0.000). Hemogram analysis revealed that leukocyte, lymphocyte, granulocyte, erythrocyte, and hemoglobin levels were lower in non-septic panleukopenic cats compared with the healthy ones (p < 0.030). Also, monocyte and mean corpuscular hemoglobin levels were lower in septic ones (p < 0.048). Serum biochemistry profiling revealed higher blood urea nitrogen, creatinine, alanine aminotransferase, lactate dehydrogenase, total bilirubin, and C-reactive protein levels in panleukopenic cats (p < 0.033). As a result, it was concluded that although the qSOFA is not sufficient to distinguish sepsis in cats, unlike dogs, in order to achieve a positive clinical outcome, when evaluated together with hematochemical variables, it may help in making early diagnosis of FP-related complications.https://doi.org/10.1515/ovs-2022-0118catfeline panleukopeniadiagnosis |
| spellingShingle | Gülersoy Erdem Erol Büşra Burcu Ok Mahmut Sevinç Mutlu Evaluation of qSOFA and variation of hematochemical profile in cats naturally infected with feline panleukopenia virus Open Veterinary Science cat feline panleukopenia diagnosis |
| title | Evaluation of qSOFA and variation of hematochemical profile in cats naturally infected with feline panleukopenia virus |
| title_full | Evaluation of qSOFA and variation of hematochemical profile in cats naturally infected with feline panleukopenia virus |
| title_fullStr | Evaluation of qSOFA and variation of hematochemical profile in cats naturally infected with feline panleukopenia virus |
| title_full_unstemmed | Evaluation of qSOFA and variation of hematochemical profile in cats naturally infected with feline panleukopenia virus |
| title_short | Evaluation of qSOFA and variation of hematochemical profile in cats naturally infected with feline panleukopenia virus |
| title_sort | evaluation of qsofa and variation of hematochemical profile in cats naturally infected with feline panleukopenia virus |
| topic | cat feline panleukopenia diagnosis |
| url | https://doi.org/10.1515/ovs-2022-0118 |
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