Modulating the activity of short arginine-tryptophan containing antibacterial peptides with N-terminal metallocenoyl groups

Modulating the activity of short arginine-tryptophan containing antibacterial peptides with N-terminal metallocenoyl groups

A series of small synthetic arginine and tryptophan containing peptides was prepared and analyzed for their antibacterial activity. The effect of N-terminal substitution with metallocenoyl groups such as ferrocene (FcCO) and ruthenocene (RcCO) was investigated. Antibacterial activity in different me...

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Bibliographic Details
Main Authors: H. Bauke Albada, Alina-Iulia Chiriac, Michaela Wenzel, Maya Penkova, Julia E. Bandow, Hans-Georg Sahl, Nils Metzler-Nolte
Format: Article
Language:English
Published: Beilstein-Institut 2012-10-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
antimicrobial peptides
arginine
medicinal organometallic chemistry
metallocenoyl
peptides
tryptophan
Online Access:https://doi.org/10.3762/bjoc.8.200

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