The Chemokine (C-C Motif) Receptor 2 Antagonist INCB3284 Reduces Fluid Requirements and Protects From Hemodynamic Decompensation During Resuscitation From Hemorrhagic Shock
OBJECTIVES:. Clinical correlations suggest that systemic chemokine (C-C motif) ligand (CCL) 2 release may contribute to blood pressure regulation and the development of hemodynamic instability during the early inflammatory response to traumatic-hemorrhagic shock. Thus, we investigated whether blocka...
Main Authors: | Anthony J. DeSantis, MD, McWayne Weche, MD, Garrett A. Enten, MS, Xianlong Gao, MD, PhD, Matthias Majetschak, MD, PhD |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer
2022-05-01
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Series: | Critical Care Explorations |
Online Access: | http://journals.lww.com/10.1097/CCE.0000000000000701 |
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