The Chemokine (C-C Motif) Receptor 2 Antagonist INCB3284 Reduces Fluid Requirements and Protects From Hemodynamic Decompensation During Resuscitation From Hemorrhagic Shock

The Chemokine (C-C Motif) Receptor 2 Antagonist INCB3284 Reduces Fluid Requirements and Protects From Hemodynamic Decompensation During Resuscitation From Hemorrhagic Shock

OBJECTIVES:. Clinical correlations suggest that systemic chemokine (C-C motif) ligand (CCL) 2 release may contribute to blood pressure regulation and the development of hemodynamic instability during the early inflammatory response to traumatic-hemorrhagic shock. Thus, we investigated whether blocka...

Full description

Bibliographic Details
Main Authors: Anthony J. DeSantis, MD, McWayne Weche, MD, Garrett A. Enten, MS, Xianlong Gao, MD, PhD, Matthias Majetschak, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2022-05-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000000701

Similar Items

Similar Items