Ensemble learning model for identifying the hallmark genes of NFκB/TNF signaling pathway in cancers

Ensemble learning model for identifying the hallmark genes of NFκB/TNF signaling pathway in cancers

Abstract Background The nuclear factor kappa B (NFκB) regulatory pathways downstream of tumor necrosis factor (TNF) play a critical role in carcinogenesis. However, the widespread influence of NFκB in cells can result in off-target effects, making it a challenging therapeutic target. Ensemble learni...

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Bibliographic Details
Main Authors:	Yin-Yuan Su, Yu-Ling Liu, Hsuan-Cheng Huang, Chen-Ching Lin
Format:	Article
Language:	English
Published:	BMC 2023-07-01
Series:	Journal of Translational Medicine
Subjects:	Ensemble learning model Carcinogenesis Nuclear factor kappa B (NFκB) Tumor necrosis factor (TNF) Triple-negative breast cancer (TNBC) Precision medicine
Online Access:	https://doi.org/10.1186/s12967-023-04355-5

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