Colorectal Cancer Heterogeneity and the Impact on Precision Medicine and Therapy Efficacy
Novel targeted therapies for metastatic colorectal cancer are needed to personalize treatments by guiding specific biomarkers selected on the genetic profile of patients. <i>RAS</i> and <i>BRAF</i> inhibitors have been developed for patients who become unresponsive to standar...
Main Authors: | Gerardo Rosati, Giuseppe Aprile, Alfredo Colombo, Stefano Cordio, Marianna Giampaglia, Alessandro Cappetta, Concetta Maria Porretto, Alfonso De Stefano, Domenico Bilancia, Antonio Avallone |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-04-01
|
Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/10/5/1035 |
Similar Items
-
Molecular Susceptibility and Treatment Challenges in Melanoma
by: Kiran Kumar Kolathur, et al.
Published: (2024-08-01) -
Somatic Mutations in Surgically Treated Colorectal Liver Metastases: An Overview
by: Jane Wang, et al.
Published: (2024-04-01) -
Developing Models to Predict <i>BRAF</i>V600E and <i>RAS</i> Mutational Status in Papillary Thyroid Carcinoma Using Clinicopathological Features and pERK1/2 Immunohistochemistry Expression
by: Agnes Stephanie Harahap, et al.
Published: (2023-10-01) -
Molecular genetic characteristics of colorectal cancer depending on the status of microsatellite instability
by: K. A. Oganyan, et al.
Published: (2022-06-01) -
<i>NTRK</i> Fusions in Sarcomas: Diagnostic Challenges and Clinical Aspects
by: Vasiliki Siozopoulou, et al.
Published: (2021-03-01)