Comparison of hyperpolarized 3He-MRI, CT based parametric response mapping, and mucus scores in asthmatics

Comparison of hyperpolarized 3He-MRI, CT based parametric response mapping, and mucus scores in asthmatics

Purpose: The purpose of this study was to anatomically correlate ventilation defects with regions of air trapping by whole lung, lung lobe, and airway segment in the context of airway mucus plugging in asthma.Methods: A total of 34 asthmatics [13M:21F, 13 mild/moderate, median age (range) of 49.5 (3...

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Main Authors: Katherine J. Carey, Peter Hotvedt, David G. Mummy, Kristine E. Lee, Loren C. Denlinger, Mark L. Schiebler, Ronald L. Sorkness, Nizar N. Jarjour, Charles R. Hatt, Craig J. Galban, Sean B. Fain
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Physiology
Subjects:
asthma
MRI
CT
gas trapping
hyperpolarized He-3
parametric response mapping (PRM)
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1178339/full

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