Health-related quality of life is related to COPD disease severity
<p>Abstract</p> <p>Background</p> <p>The aim of this study was to evaluate the association between health-related quality of life (HRQL) and disease severity using lung function measures.</p> <p>Methods</p> <p>A survey was performed in subjects w...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2005-09-01
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| Series: | Health and Quality of Life Outcomes |
| Subjects: | |
| Online Access: | http://www.hqlo.com/content/3/1/56 |
| _version_ | 1818663607601201152 |
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| author | Rönmark Eva Jansson Sven-Arne Lindberg Anne Ståhl Elisabeth Svensson Klas Andersson Fredrik Löfdahl Claes-Göran Lundbäck Bo |
| author_facet | Rönmark Eva Jansson Sven-Arne Lindberg Anne Ståhl Elisabeth Svensson Klas Andersson Fredrik Löfdahl Claes-Göran Lundbäck Bo |
| author_sort | Rönmark Eva |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>The aim of this study was to evaluate the association between health-related quality of life (HRQL) and disease severity using lung function measures.</p> <p>Methods</p> <p>A survey was performed in subjects with COPD in Sweden. 168 subjects (70 women, mean age 64.3 years) completed the generic HRQL questionnaire, the Short Form 36 (SF-36), the disease-specific HRQL questionnaire; the St George's Respiratory Questionnaire (SGRQ), and the utility measure, the EQ-5D. The subjects were divided into four severity groups according to FEV<sub>1 </sub>per cent of predicted normal using two clinical guidelines: GOLD and BTS. Age, gender, smoking status and socio-economic group were regarded as confounders.</p> <p>Results</p> <p>The COPD severity grades affected the SGRQ Total scores, varying from 25 to 53 (GOLD p = 0.0005) and from 25 to 45 (BTS p = 0.0023). The scores for SF-36 Physical were significantly associated with COPD severity (GOLD p = 0.0059, BTS p = 0.032). No significant association were noticed for the SF-36, Mental Component Summary scores and COPD severity. Scores for EQ-5D VAS varied from 73 to 37 (GOLD I-IV p = 0.0001) and from 73 to 50 (BTS 0-III p = 0.0007). The SGRQ Total score was significant between age groups (p = 0.0047). No significant differences in HRQL with regard to gender, smoking status or socio-economic group were noticed.</p> <p>Conclusion</p> <p>The results show that HRQL in COPD deteriorates with disease severity and with age. These data show a relationship between HRQL and disease severity obtained by lung function.</p> |
| first_indexed | 2024-12-17T05:19:32Z |
| format | Article |
| id | doaj.art-113ad0323629496ab666124b004d861d |
| institution | Directory Open Access Journal |
| issn | 1477-7525 |
| language | English |
| last_indexed | 2024-12-17T05:19:32Z |
| publishDate | 2005-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Health and Quality of Life Outcomes |
| spelling | doaj.art-113ad0323629496ab666124b004d861d2022-12-21T22:02:01ZengBMCHealth and Quality of Life Outcomes1477-75252005-09-01315610.1186/1477-7525-3-56Health-related quality of life is related to COPD disease severityRönmark EvaJansson Sven-ArneLindberg AnneStåhl ElisabethSvensson KlasAndersson FredrikLöfdahl Claes-GöranLundbäck Bo<p>Abstract</p> <p>Background</p> <p>The aim of this study was to evaluate the association between health-related quality of life (HRQL) and disease severity using lung function measures.</p> <p>Methods</p> <p>A survey was performed in subjects with COPD in Sweden. 168 subjects (70 women, mean age 64.3 years) completed the generic HRQL questionnaire, the Short Form 36 (SF-36), the disease-specific HRQL questionnaire; the St George's Respiratory Questionnaire (SGRQ), and the utility measure, the EQ-5D. The subjects were divided into four severity groups according to FEV<sub>1 </sub>per cent of predicted normal using two clinical guidelines: GOLD and BTS. Age, gender, smoking status and socio-economic group were regarded as confounders.</p> <p>Results</p> <p>The COPD severity grades affected the SGRQ Total scores, varying from 25 to 53 (GOLD p = 0.0005) and from 25 to 45 (BTS p = 0.0023). The scores for SF-36 Physical were significantly associated with COPD severity (GOLD p = 0.0059, BTS p = 0.032). No significant association were noticed for the SF-36, Mental Component Summary scores and COPD severity. Scores for EQ-5D VAS varied from 73 to 37 (GOLD I-IV p = 0.0001) and from 73 to 50 (BTS 0-III p = 0.0007). The SGRQ Total score was significant between age groups (p = 0.0047). No significant differences in HRQL with regard to gender, smoking status or socio-economic group were noticed.</p> <p>Conclusion</p> <p>The results show that HRQL in COPD deteriorates with disease severity and with age. These data show a relationship between HRQL and disease severity obtained by lung function.</p>http://www.hqlo.com/content/3/1/56Health-related quality of lifeCOPDdisease severityepidemiological, Global Initiative for Chronic Obstructive Lung Disease (GOLD)St George's Respiratory Questionnaire (SGRQ) |
| spellingShingle | Rönmark Eva Jansson Sven-Arne Lindberg Anne Ståhl Elisabeth Svensson Klas Andersson Fredrik Löfdahl Claes-Göran Lundbäck Bo Health-related quality of life is related to COPD disease severity Health and Quality of Life Outcomes Health-related quality of life COPD disease severity epidemiological, Global Initiative for Chronic Obstructive Lung Disease (GOLD) St George's Respiratory Questionnaire (SGRQ) |
| title | Health-related quality of life is related to COPD disease severity |
| title_full | Health-related quality of life is related to COPD disease severity |
| title_fullStr | Health-related quality of life is related to COPD disease severity |
| title_full_unstemmed | Health-related quality of life is related to COPD disease severity |
| title_short | Health-related quality of life is related to COPD disease severity |
| title_sort | health related quality of life is related to copd disease severity |
| topic | Health-related quality of life COPD disease severity epidemiological, Global Initiative for Chronic Obstructive Lung Disease (GOLD) St George's Respiratory Questionnaire (SGRQ) |
| url | http://www.hqlo.com/content/3/1/56 |
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