Extrusion-Based 3D Printing of Microfluidic Devices for Chemical and Biomedical Applications: A Topical Review

One of the most widespread additive manufacturing (AM) technologies is fused deposition modelling (FDM), also known as fused filament fabrication (FFF) or extrusion-based AM. The main reasons for its success are low costs, very simple machine structure, and a wide variety of available materials. How...

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Main Authors: Daniela Pranzo, Piero Larizza, Daniel Filippini, Gianluca Percoco
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Micromachines
Subjects:
Online Access:http://www.mdpi.com/2072-666X/9/8/374
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author Daniela Pranzo
Piero Larizza
Daniel Filippini
Gianluca Percoco
author_facet Daniela Pranzo
Piero Larizza
Daniel Filippini
Gianluca Percoco
author_sort Daniela Pranzo
collection DOAJ
description One of the most widespread additive manufacturing (AM) technologies is fused deposition modelling (FDM), also known as fused filament fabrication (FFF) or extrusion-based AM. The main reasons for its success are low costs, very simple machine structure, and a wide variety of available materials. However, one of the main limitations of the process is its accuracy and finishing. In spite of this, FDM is finding more and more applications, including in the world of micro-components. In this world, one of the most interesting topics is represented by microfluidic reactors for chemical and biomedical applications. The present review focusses on this research topic from a process point of view, describing at first the platforms and materials and then deepening the most relevant applications.
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spelling doaj.art-11419d4fbc2b4f6f9b4ee9b2c8be3b672022-12-21T23:31:51ZengMDPI AGMicromachines2072-666X2018-07-019837410.3390/mi9080374mi9080374Extrusion-Based 3D Printing of Microfluidic Devices for Chemical and Biomedical Applications: A Topical ReviewDaniela Pranzo0Piero Larizza1Daniel Filippini2Gianluca Percoco3Masmec Biomed, Masmec S.p.A. Division, 70026 Modugno (Bari), ItalyMasmec Biomed, Masmec S.p.A. Division, 70026 Modugno (Bari), ItalyOptical Devices Lab, IFM, Linköping University, 58183 Linköping, SwedenDepartment of Mechanics, Mathematics and Management, Polytechnic University of Bari, 70126 Bari, ItalyOne of the most widespread additive manufacturing (AM) technologies is fused deposition modelling (FDM), also known as fused filament fabrication (FFF) or extrusion-based AM. The main reasons for its success are low costs, very simple machine structure, and a wide variety of available materials. However, one of the main limitations of the process is its accuracy and finishing. In spite of this, FDM is finding more and more applications, including in the world of micro-components. In this world, one of the most interesting topics is represented by microfluidic reactors for chemical and biomedical applications. The present review focusses on this research topic from a process point of view, describing at first the platforms and materials and then deepening the most relevant applications.http://www.mdpi.com/2072-666X/9/8/374FFFFDM3D printingbiomedical deviceschemical reactorsmicrofluidicslab-on-a-chip (LOC)
spellingShingle Daniela Pranzo
Piero Larizza
Daniel Filippini
Gianluca Percoco
Extrusion-Based 3D Printing of Microfluidic Devices for Chemical and Biomedical Applications: A Topical Review
Micromachines
FFF
FDM
3D printing
biomedical devices
chemical reactors
microfluidics
lab-on-a-chip (LOC)
title Extrusion-Based 3D Printing of Microfluidic Devices for Chemical and Biomedical Applications: A Topical Review
title_full Extrusion-Based 3D Printing of Microfluidic Devices for Chemical and Biomedical Applications: A Topical Review
title_fullStr Extrusion-Based 3D Printing of Microfluidic Devices for Chemical and Biomedical Applications: A Topical Review
title_full_unstemmed Extrusion-Based 3D Printing of Microfluidic Devices for Chemical and Biomedical Applications: A Topical Review
title_short Extrusion-Based 3D Printing of Microfluidic Devices for Chemical and Biomedical Applications: A Topical Review
title_sort extrusion based 3d printing of microfluidic devices for chemical and biomedical applications a topical review
topic FFF
FDM
3D printing
biomedical devices
chemical reactors
microfluidics
lab-on-a-chip (LOC)
url http://www.mdpi.com/2072-666X/9/8/374
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