Referential Values of Testicular Volume Measured by Ultrasonography in Normal Children and Adolescents: Z-Score Establishment

Objective: To establish Z-score regression equation derived from age for testicular volume measured by ultrasonography in normal boys aged 0 to 18 years old.Method: The length (L), width (W), and height (H) of 3,328 testicles from 1,664 Chinese boys were measured by ultrasonography. Lambert's f...

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Main Authors: Chen Liu, Xiao Liu, Xiangxiang Zhang, Boyang Yang, Lan Huang, Hongying Wang, Hongkui Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2021.648711/full
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author Chen Liu
Xiao Liu
Xiangxiang Zhang
Boyang Yang
Lan Huang
Hongying Wang
Hongkui Yu
author_facet Chen Liu
Xiao Liu
Xiangxiang Zhang
Boyang Yang
Lan Huang
Hongying Wang
Hongkui Yu
author_sort Chen Liu
collection DOAJ
description Objective: To establish Z-score regression equation derived from age for testicular volume measured by ultrasonography in normal boys aged 0 to 18 years old.Method: The length (L), width (W), and height (H) of 3,328 testicles from 1,664 Chinese boys were measured by ultrasonography. Lambert's formula: L × W × H × 0.71 was used to calculate testicular volume. Z-score regression equation derived from age was established by regression analysis of predicted values of testicular volume and standard deviations.Result: There was no significant difference between left and right testicular volumes. Testicular volume was positively correlated with age, and logarithmic transformation of testicular volume can show a fine curve fit with age. To establish Z-score regression equation derived from age, the predicted values of testicular volume used cubic regression equations, and the standard deviation used square regression equations. The Z-score regression equation derived from age was calculated by the formula: z = [lg (L × W × H × 0.71) – (−0.3524-0.01759 × x+0.009417 × x2-0.0001840 × x3)]/(0.1059+0.01434 × x-0.0005324 × x2).Conclusion: The current study provided a reference value for testicular volume of boys aged 0 to 18 years old. Z-score regression equation derived from age for testicular volume can be established. Z-score will be of great value for the testicular development assessment and disease diagnosis and follow-up.
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spelling doaj.art-1142c79292a04f9d8af4a7a818eef8872022-12-21T20:33:03ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602021-03-01910.3389/fped.2021.648711648711Referential Values of Testicular Volume Measured by Ultrasonography in Normal Children and Adolescents: Z-Score EstablishmentChen Liu0Xiao Liu1Xiangxiang Zhang2Boyang Yang3Lan Huang4Hongying Wang5Hongkui Yu6Department of Ultrasonography, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, ChinaDepartment of Ultrasonography, Shenzhen Hospital of Guangzhou University of Chinese Medicine, Shenzhen, ChinaDepartment of Ultrasonography, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, ChinaDepartment of Ultrasonography, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, ChinaDepartment of Ultrasonography, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, ChinaDepartment of Ultrasonography, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, ChinaDepartment of Ultrasonography, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, ChinaObjective: To establish Z-score regression equation derived from age for testicular volume measured by ultrasonography in normal boys aged 0 to 18 years old.Method: The length (L), width (W), and height (H) of 3,328 testicles from 1,664 Chinese boys were measured by ultrasonography. Lambert's formula: L × W × H × 0.71 was used to calculate testicular volume. Z-score regression equation derived from age was established by regression analysis of predicted values of testicular volume and standard deviations.Result: There was no significant difference between left and right testicular volumes. Testicular volume was positively correlated with age, and logarithmic transformation of testicular volume can show a fine curve fit with age. To establish Z-score regression equation derived from age, the predicted values of testicular volume used cubic regression equations, and the standard deviation used square regression equations. The Z-score regression equation derived from age was calculated by the formula: z = [lg (L × W × H × 0.71) – (−0.3524-0.01759 × x+0.009417 × x2-0.0001840 × x3)]/(0.1059+0.01434 × x-0.0005324 × x2).Conclusion: The current study provided a reference value for testicular volume of boys aged 0 to 18 years old. Z-score regression equation derived from age for testicular volume can be established. Z-score will be of great value for the testicular development assessment and disease diagnosis and follow-up.https://www.frontiersin.org/articles/10.3389/fped.2021.648711/fulltesticular volumeZ-scoreultrasonographychildrenreferential values
spellingShingle Chen Liu
Xiao Liu
Xiangxiang Zhang
Boyang Yang
Lan Huang
Hongying Wang
Hongkui Yu
Referential Values of Testicular Volume Measured by Ultrasonography in Normal Children and Adolescents: Z-Score Establishment
Frontiers in Pediatrics
testicular volume
Z-score
ultrasonography
children
referential values
title Referential Values of Testicular Volume Measured by Ultrasonography in Normal Children and Adolescents: Z-Score Establishment
title_full Referential Values of Testicular Volume Measured by Ultrasonography in Normal Children and Adolescents: Z-Score Establishment
title_fullStr Referential Values of Testicular Volume Measured by Ultrasonography in Normal Children and Adolescents: Z-Score Establishment
title_full_unstemmed Referential Values of Testicular Volume Measured by Ultrasonography in Normal Children and Adolescents: Z-Score Establishment
title_short Referential Values of Testicular Volume Measured by Ultrasonography in Normal Children and Adolescents: Z-Score Establishment
title_sort referential values of testicular volume measured by ultrasonography in normal children and adolescents z score establishment
topic testicular volume
Z-score
ultrasonography
children
referential values
url https://www.frontiersin.org/articles/10.3389/fped.2021.648711/full
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