Bioactive Natural Products for Chemical Control of Microorganisms: Scientific Prospecting (2001–2021) and Systematic Review

The inappropriate use of synthetic antibiotics has become a global public health problem. Therefore, the study of new alternatives for the treatment of infectious diseases is relevant and natural bioactive products are on the rise. This study conducted a scientific prospection of bioactive natural p...

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Main Authors: Bruno Fonsêca Feitosa, Charlene Maria de Alcântara, Amanda Beatriz Sales de Lima, Adriano Sant’Ana Silva, Alfredina dos Santos Araújo, Mônica Tejo Cavalcanti, Edna Mori, Isaac Moura Araújo, Pablo Antonio Maia de Farias, Polrat Wilairatana, Henrique Douglas Melo Coutinho
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/18/5917
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author Bruno Fonsêca Feitosa
Charlene Maria de Alcântara
Amanda Beatriz Sales de Lima
Adriano Sant’Ana Silva
Alfredina dos Santos Araújo
Mônica Tejo Cavalcanti
Edna Mori
Isaac Moura Araújo
Pablo Antonio Maia de Farias
Polrat Wilairatana
Henrique Douglas Melo Coutinho
author_facet Bruno Fonsêca Feitosa
Charlene Maria de Alcântara
Amanda Beatriz Sales de Lima
Adriano Sant’Ana Silva
Alfredina dos Santos Araújo
Mônica Tejo Cavalcanti
Edna Mori
Isaac Moura Araújo
Pablo Antonio Maia de Farias
Polrat Wilairatana
Henrique Douglas Melo Coutinho
author_sort Bruno Fonsêca Feitosa
collection DOAJ
description The inappropriate use of synthetic antibiotics has become a global public health problem. Therefore, the study of new alternatives for the treatment of infectious diseases is relevant and natural bioactive products are on the rise. This study conducted a scientific prospection of bioactive natural products with promising applications in the chemical control of microorganisms. A systematic review of the most recent articles was performed according to the following three steps: (i) eligibility assessment, (ii) screening, and (iii) inclusion of articles and information extraction. There has been an increase in the number of scientific publications on bioactive natural products for microbial control in the CAPES and SciELO databases (2001–2021). Seventeen relevant articles were included, most of which focused on extracts. Ascorbic acid, chlorogenic acid, chrysin, and quercetin were the most cited compounds. Natural products were shown to be effective in inhibiting more than 30 microorganisms. A discussion was presented on the research trends.
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spelling doaj.art-114538f4eb334f8f8094f4406e56b9712023-11-23T18:01:08ZengMDPI AGMolecules1420-30492022-09-012718591710.3390/molecules27185917Bioactive Natural Products for Chemical Control of Microorganisms: Scientific Prospecting (2001–2021) and Systematic ReviewBruno Fonsêca Feitosa0Charlene Maria de Alcântara1Amanda Beatriz Sales de Lima2Adriano Sant’Ana Silva3Alfredina dos Santos Araújo4Mônica Tejo Cavalcanti5Edna Mori6Isaac Moura Araújo7Pablo Antonio Maia de Farias8Polrat Wilairatana9Henrique Douglas Melo Coutinho10Faculty of Food Engineering, State University of Campinas, Monteiro Lobato, 80, University City “Zeferino Vaz”, Campinas 13083-862, SP, BrazilAcademic Unit of Food Technology, Federal University of Campina Grande, Jairo Vieira Feitosa, 1770, Pombal 58840-000, Pereiros, PB, BrazilDepartment of Rural and Animal Technology, State University of Southwest Bahia, Praça Primavera, 40, Itapetinga 45700-000, BA, BrazilAcademic Unit of Food Technology, Federal University of Campina Grande, Jairo Vieira Feitosa, 1770, Pombal 58840-000, Pereiros, PB, BrazilAcademic Unit of Food Technology, Federal University of Campina Grande, Jairo Vieira Feitosa, 1770, Pombal 58840-000, Pereiros, PB, BrazilNational Institute of the Semiarid Region, Francisco Lopes de Almeida, Serrotão, Campina Grande 58434-700, PB, BrazilCECAPE College. Av. Padre Cícero, 3917, Juazeiro do Norte 63024-015, CE, BrazilDepartment of Biological Chemistry, Regional University of Cariri, Av. Cel. Antonio Luiz, 1161, Crato 63105-000, CE, BrazilDepartment of Biological Chemistry, Regional University of Cariri, Av. Cel. Antonio Luiz, 1161, Crato 63105-000, CE, BrazilDepartment of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, ThailandDepartment of Biological Chemistry, Regional University of Cariri, Av. Cel. Antonio Luiz, 1161, Crato 63105-000, CE, BrazilThe inappropriate use of synthetic antibiotics has become a global public health problem. Therefore, the study of new alternatives for the treatment of infectious diseases is relevant and natural bioactive products are on the rise. This study conducted a scientific prospection of bioactive natural products with promising applications in the chemical control of microorganisms. A systematic review of the most recent articles was performed according to the following three steps: (i) eligibility assessment, (ii) screening, and (iii) inclusion of articles and information extraction. There has been an increase in the number of scientific publications on bioactive natural products for microbial control in the CAPES and SciELO databases (2001–2021). Seventeen relevant articles were included, most of which focused on extracts. Ascorbic acid, chlorogenic acid, chrysin, and quercetin were the most cited compounds. Natural products were shown to be effective in inhibiting more than 30 microorganisms. A discussion was presented on the research trends.https://www.mdpi.com/1420-3049/27/18/5917anti-bacterialbioactive compoundsessential oilsextractsscientific articles
spellingShingle Bruno Fonsêca Feitosa
Charlene Maria de Alcântara
Amanda Beatriz Sales de Lima
Adriano Sant’Ana Silva
Alfredina dos Santos Araújo
Mônica Tejo Cavalcanti
Edna Mori
Isaac Moura Araújo
Pablo Antonio Maia de Farias
Polrat Wilairatana
Henrique Douglas Melo Coutinho
Bioactive Natural Products for Chemical Control of Microorganisms: Scientific Prospecting (2001–2021) and Systematic Review
Molecules
anti-bacterial
bioactive compounds
essential oils
extracts
scientific articles
title Bioactive Natural Products for Chemical Control of Microorganisms: Scientific Prospecting (2001–2021) and Systematic Review
title_full Bioactive Natural Products for Chemical Control of Microorganisms: Scientific Prospecting (2001–2021) and Systematic Review
title_fullStr Bioactive Natural Products for Chemical Control of Microorganisms: Scientific Prospecting (2001–2021) and Systematic Review
title_full_unstemmed Bioactive Natural Products for Chemical Control of Microorganisms: Scientific Prospecting (2001–2021) and Systematic Review
title_short Bioactive Natural Products for Chemical Control of Microorganisms: Scientific Prospecting (2001–2021) and Systematic Review
title_sort bioactive natural products for chemical control of microorganisms scientific prospecting 2001 2021 and systematic review
topic anti-bacterial
bioactive compounds
essential oils
extracts
scientific articles
url https://www.mdpi.com/1420-3049/27/18/5917
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