Expression- and splicing-based multi-tissue transcriptome-wide association studies identified multiple genes for breast cancer by estrogen-receptor status

Expression- and splicing-based multi-tissue transcriptome-wide association studies identified multiple genes for breast cancer by estrogen-receptor status

Abstract Background Although several transcriptome-wide association studies (TWASs) have been performed to identify genes associated with overall breast cancer (BC) risk, only a few TWAS have explored the differences in estrogen receptor-positive (ER+) and estrogen receptor-negative (ER-) breast can...

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Bibliographic Details
Main Authors: Julian C. McClellan, James L. Li, Guimin Gao, Dezheng Huo
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Breast Cancer Research
Subjects:
Breast
Cancer
TWAS
Estrogen
Receptor
Splicing
Online Access:https://doi.org/10.1186/s13058-024-01809-6

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