Myeloid-derived suppressor cells exacerbate poly(I:C)-induced lung inflammation in mice with renal injury and older mice

Myeloid-derived suppressor cells exacerbate poly(I:C)-induced lung inflammation in mice with renal injury and older mice

Viral pneumonia is a global health burden with a high mortality rate, especially in the elderly and in patients with underlying diseases. Recent studies have found that myeloid-derived suppressor cells (MDSCs) are abundant in these patient groups; however, their roles in the progression of viral pne...

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Bibliographic Details
Main Authors: Zhiqi Xie, Haoyang Zhou, Masanori Obana, Yasushi Fujio, Naoki Okada, Masashi Tachibana
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
MDSC
poly(I:C)
lung inflammation
aging
renal ischemia/reperfusion injury
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1243851/full

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