Atypical varicella-zoster virus reactivation: a case report
Varicella-zoster virus (VZV) commonly causes benign skin manifestations in children; it then establishes a latent infection and may reactivate, causing herpes zoster. The most common zoster complication is postherpetic neuralgia, but complications can also occur without a rash. VZV infection may cau...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SMC MEDIA SRL
2023-08-01
|
| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/3945 |
| _version_ | 1797692508009922560 |
|---|---|
| author | Francesca Salvotti Simone Trapletti Giulia Chiarini Maurizio Castellano Maria Lorenza Muiesan |
| author_facet | Francesca Salvotti Simone Trapletti Giulia Chiarini Maurizio Castellano Maria Lorenza Muiesan |
| author_sort | Francesca Salvotti |
| collection | DOAJ |
| description | Varicella-zoster virus (VZV) commonly causes benign skin manifestations in children; it then establishes a latent infection and may reactivate, causing herpes zoster. The most common zoster complication is postherpetic neuralgia, but complications can also occur without a rash. VZV infection may cause neurological manifestations and even vasculopathy may occur, in both primary and reactivated VZV infection. Thrombotic complications are mainly described in children, while a few case reports have described cerebral venous sinus thrombosis (CVST), deep-vein thrombosis of the lower limbs and pulmonary embolism in adults. In this article we report the case of a young woman who developed systemic thromboembolic sequelae due to a hypercoagulable state following VZV reactivation. She had deep venous lower-limb thrombosis extended to the inferior vena cava (IVC), massive pulmonary embolism and CVST. Moreover, VZV reactivation caused an acute hepatitis and clinical manifestations suggesting viral encephalitis. |
| first_indexed | 2024-03-12T02:28:39Z |
| format | Article |
| id | doaj.art-1155ae97bdd54e9a9b21767353fcc536 |
| institution | Directory Open Access Journal |
| issn | 2284-2594 |
| language | English |
| last_indexed | 2024-03-12T02:28:39Z |
| publishDate | 2023-08-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj.art-1155ae97bdd54e9a9b21767353fcc5362023-09-05T09:56:45ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942023-08-0110.12890/2023_0039453480Atypical varicella-zoster virus reactivation: a case reportFrancesca Salvotti0Simone Trapletti1Giulia Chiarini2Maurizio Castellano3Maria Lorenza Muiesan4Department of Medicine, ASST Spedali Civili, Brescia, Italy; Internal Medicine, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, ItalyDepartment of Medicine, ASST Spedali Civili, Brescia, Italy; Internal Medicine, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, ItalyDepartment of Medicine, ASST Spedali Civili, Brescia, Italy; Internal Medicine, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, ItalyDepartment of Medicine, ASST Spedali Civili, Brescia, Italy; Internal Medicine, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, ItalyDepartment of Medicine, ASST Spedali Civili, Brescia, Italy; Internal Medicine, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, ItalyVaricella-zoster virus (VZV) commonly causes benign skin manifestations in children; it then establishes a latent infection and may reactivate, causing herpes zoster. The most common zoster complication is postherpetic neuralgia, but complications can also occur without a rash. VZV infection may cause neurological manifestations and even vasculopathy may occur, in both primary and reactivated VZV infection. Thrombotic complications are mainly described in children, while a few case reports have described cerebral venous sinus thrombosis (CVST), deep-vein thrombosis of the lower limbs and pulmonary embolism in adults. In this article we report the case of a young woman who developed systemic thromboembolic sequelae due to a hypercoagulable state following VZV reactivation. She had deep venous lower-limb thrombosis extended to the inferior vena cava (IVC), massive pulmonary embolism and CVST. Moreover, VZV reactivation caused an acute hepatitis and clinical manifestations suggesting viral encephalitis.https://www.ejcrim.com/index.php/EJCRIM/article/view/3945varicella-zoster viruszoster sine herpetecerebral venous sinus thrombosispulmonary embolismencephalitis |
| spellingShingle | Francesca Salvotti Simone Trapletti Giulia Chiarini Maurizio Castellano Maria Lorenza Muiesan Atypical varicella-zoster virus reactivation: a case report European Journal of Case Reports in Internal Medicine varicella-zoster virus zoster sine herpete cerebral venous sinus thrombosis pulmonary embolism encephalitis |
| title | Atypical varicella-zoster virus reactivation: a case report |
| title_full | Atypical varicella-zoster virus reactivation: a case report |
| title_fullStr | Atypical varicella-zoster virus reactivation: a case report |
| title_full_unstemmed | Atypical varicella-zoster virus reactivation: a case report |
| title_short | Atypical varicella-zoster virus reactivation: a case report |
| title_sort | atypical varicella zoster virus reactivation a case report |
| topic | varicella-zoster virus zoster sine herpete cerebral venous sinus thrombosis pulmonary embolism encephalitis |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/3945 |
| work_keys_str_mv | AT francescasalvotti atypicalvaricellazostervirusreactivationacasereport AT simonetrapletti atypicalvaricellazostervirusreactivationacasereport AT giuliachiarini atypicalvaricellazostervirusreactivationacasereport AT mauriziocastellano atypicalvaricellazostervirusreactivationacasereport AT marialorenzamuiesan atypicalvaricellazostervirusreactivationacasereport |