Prevalence of Antibiotic Prescription in Patients with Acute Rhinosinusitis Treated by General Practitioners and Otolaryngologists in Germany—A Retrospective Cohort Study
(1) Background: The goal of this retrospective cohort study, based on real-world data and conducted in Germany, was to investigate the prevalence of antibiotic (AB) prescription in patients with acute rhinosinusitis (ARS). (2) Methods: Data from the Disease Analyzer database were used for this cross...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-11-01
|
| Series: | Antibiotics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6382/11/11/1576 |
| _version_ | 1797469319931625472 |
|---|---|
| author | Claudia B. Bittner Michael Plach Hubert Steindl Dimitri Abramov-Sommariva Christoph Abels Karel Kostev |
| author_facet | Claudia B. Bittner Michael Plach Hubert Steindl Dimitri Abramov-Sommariva Christoph Abels Karel Kostev |
| author_sort | Claudia B. Bittner |
| collection | DOAJ |
| description | (1) Background: The goal of this retrospective cohort study, based on real-world data and conducted in Germany, was to investigate the prevalence of antibiotic (AB) prescription in patients with acute rhinosinusitis (ARS). (2) Methods: Data from the Disease Analyzer database were used for this cross-sectional study. Patients aged ≥18 years diagnosed with acute sinusitis by general practitioners (GPs) and ear, nose, throat (ENT) specialists between January 2012 and December 2020 were included. The main outcome of the study was the proportion of patients with ARS who received an AB prescription on the day of diagnosis or within three days afterwards. The proportion was estimated separately for patients treated by GPs and ENTs, and also for five age groups, as well as women and men. (3) Results: In total, 308,095 patients were diagnosed with ARS (187,838 by GPs and 120,257 by ENTs). 50.9% of patients treated by GPs and 50.0% treated by ENTs received an AB prescription. AB prevalence increased with age from 46.9% in the age group 18–30 years to 55.5% in the age group > 60 years. (4) Conclusions: We have shown a high prevalence of potentially inappropriate AB prescription for adult patients with ARS in both GP and ENT practices and also among both women and men and in several age groups. There is an urgent need for interventions to reduce inappropriate AB use. |
| first_indexed | 2024-03-09T19:18:45Z |
| format | Article |
| id | doaj.art-11571730ca2a4031b32834a91de9818a |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-09T19:18:45Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-11571730ca2a4031b32834a91de9818a2023-11-24T03:28:38ZengMDPI AGAntibiotics2079-63822022-11-011111157610.3390/antibiotics11111576Prevalence of Antibiotic Prescription in Patients with Acute Rhinosinusitis Treated by General Practitioners and Otolaryngologists in Germany—A Retrospective Cohort StudyClaudia B. Bittner0Michael Plach1Hubert Steindl2Dimitri Abramov-Sommariva3Christoph Abels4Karel Kostev5Research & Development, Bionorica SE, 92318 Neumarkt in der Oberpfalz, GermanyResearch & Development, Bionorica SE, 92318 Neumarkt in der Oberpfalz, GermanyResearch & Development, Bionorica SE, 92318 Neumarkt in der Oberpfalz, GermanyResearch & Development, Bionorica SE, 92318 Neumarkt in der Oberpfalz, GermanyResearch & Development, Bionorica SE, 92318 Neumarkt in der Oberpfalz, GermanyEpidemiology, IQVIA, 60549 Frankfurt am Main, Germany(1) Background: The goal of this retrospective cohort study, based on real-world data and conducted in Germany, was to investigate the prevalence of antibiotic (AB) prescription in patients with acute rhinosinusitis (ARS). (2) Methods: Data from the Disease Analyzer database were used for this cross-sectional study. Patients aged ≥18 years diagnosed with acute sinusitis by general practitioners (GPs) and ear, nose, throat (ENT) specialists between January 2012 and December 2020 were included. The main outcome of the study was the proportion of patients with ARS who received an AB prescription on the day of diagnosis or within three days afterwards. The proportion was estimated separately for patients treated by GPs and ENTs, and also for five age groups, as well as women and men. (3) Results: In total, 308,095 patients were diagnosed with ARS (187,838 by GPs and 120,257 by ENTs). 50.9% of patients treated by GPs and 50.0% treated by ENTs received an AB prescription. AB prevalence increased with age from 46.9% in the age group 18–30 years to 55.5% in the age group > 60 years. (4) Conclusions: We have shown a high prevalence of potentially inappropriate AB prescription for adult patients with ARS in both GP and ENT practices and also among both women and men and in several age groups. There is an urgent need for interventions to reduce inappropriate AB use.https://www.mdpi.com/2079-6382/11/11/1576acute rhinosinusitisantibioticgeneral practitionersotolaryngologistphytopharmaceutical |
| spellingShingle | Claudia B. Bittner Michael Plach Hubert Steindl Dimitri Abramov-Sommariva Christoph Abels Karel Kostev Prevalence of Antibiotic Prescription in Patients with Acute Rhinosinusitis Treated by General Practitioners and Otolaryngologists in Germany—A Retrospective Cohort Study Antibiotics acute rhinosinusitis antibiotic general practitioners otolaryngologist phytopharmaceutical |
| title | Prevalence of Antibiotic Prescription in Patients with Acute Rhinosinusitis Treated by General Practitioners and Otolaryngologists in Germany—A Retrospective Cohort Study |
| title_full | Prevalence of Antibiotic Prescription in Patients with Acute Rhinosinusitis Treated by General Practitioners and Otolaryngologists in Germany—A Retrospective Cohort Study |
| title_fullStr | Prevalence of Antibiotic Prescription in Patients with Acute Rhinosinusitis Treated by General Practitioners and Otolaryngologists in Germany—A Retrospective Cohort Study |
| title_full_unstemmed | Prevalence of Antibiotic Prescription in Patients with Acute Rhinosinusitis Treated by General Practitioners and Otolaryngologists in Germany—A Retrospective Cohort Study |
| title_short | Prevalence of Antibiotic Prescription in Patients with Acute Rhinosinusitis Treated by General Practitioners and Otolaryngologists in Germany—A Retrospective Cohort Study |
| title_sort | prevalence of antibiotic prescription in patients with acute rhinosinusitis treated by general practitioners and otolaryngologists in germany a retrospective cohort study |
| topic | acute rhinosinusitis antibiotic general practitioners otolaryngologist phytopharmaceutical |
| url | https://www.mdpi.com/2079-6382/11/11/1576 |
| work_keys_str_mv | AT claudiabbittner prevalenceofantibioticprescriptioninpatientswithacuterhinosinusitistreatedbygeneralpractitionersandotolaryngologistsingermanyaretrospectivecohortstudy AT michaelplach prevalenceofantibioticprescriptioninpatientswithacuterhinosinusitistreatedbygeneralpractitionersandotolaryngologistsingermanyaretrospectivecohortstudy AT hubertsteindl prevalenceofantibioticprescriptioninpatientswithacuterhinosinusitistreatedbygeneralpractitionersandotolaryngologistsingermanyaretrospectivecohortstudy AT dimitriabramovsommariva prevalenceofantibioticprescriptioninpatientswithacuterhinosinusitistreatedbygeneralpractitionersandotolaryngologistsingermanyaretrospectivecohortstudy AT christophabels prevalenceofantibioticprescriptioninpatientswithacuterhinosinusitistreatedbygeneralpractitionersandotolaryngologistsingermanyaretrospectivecohortstudy AT karelkostev prevalenceofantibioticprescriptioninpatientswithacuterhinosinusitistreatedbygeneralpractitionersandotolaryngologistsingermanyaretrospectivecohortstudy |