Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet

Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet

Vitamin C (vitC) deficiency has been associated with an increased risk of cardiovascular disease; while several putative mechanistic links have been proposed, functional evidence supporting a causal relationship is scarce. In this study, we investigated how vitC deficiency affects coronary artery va...

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Bibliographic Details
Main Authors: Gry Freja Skovsted, Josephine Skat-Rørdam, Amalie Pihl Frøkiær, Henrik Elvang Jensen, Pernille Tveden-Nyborg, Jens Lykkesfeldt
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Antioxidants
Subjects:
vitamin C
atherosclerosis
coronary arteries
guinea pig model
wire myography
Online Access:https://www.mdpi.com/2076-3921/11/11/2226

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