Firocoxib as a Potential Neoadjuvant Treatment in Canine Patients with Triple-Negative Mammary Gland Tumors

Firocoxib as a Potential Neoadjuvant Treatment in Canine Patients with Triple-Negative Mammary Gland Tumors

This study aimed to investigate the pro-apoptotic effects of NSAID (Previcox<sup>®</sup>) in vitro and in vivo. Two CMT cell lines, one from the primary tumor and one from bone metastasis, were treated with firocoxib and MTT assay was performed to determine the half-maximal inhibitory co...

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Bibliographic Details
Main Authors: Andressa Brandi, Patricia de Faria Lainetti, Fabiana Elias, Marcela Marcondes Pinto Rodrigues, Livia Fagundes Moraes, Renée Laufer-Amorim, Laíza Sartori de Camargo, Cristina de Oliveira Massoco Salles Gomes, Carlos Eduardo Fonseca-Alves
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Animals
Subjects:
cyclooxygenase-2
caspase-3
chemotherapy
nonsteroidal anti-inflammatory drug
Online Access:https://www.mdpi.com/2076-2615/13/1/60

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