Design of a multi-epitope vaccine against six Nocardia species based on reverse vaccinology combined with immunoinformatics

Design of a multi-epitope vaccine against six Nocardia species based on reverse vaccinology combined with immunoinformatics

BackgroundNocardia genus, a complex group of species classified to be aerobic actinomycete, can lead to severe concurrent infection as well as disseminated infection, typically in immunocompromised patients. With the expansion of the susceptible population, the incidence of Nocardia has been gradual...

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Bibliographic Details
Main Authors: Fei Zhu, Caixia Tan, Chunhui Li, Shiyang Ma, Haicheng Wen, Hang Yang, Mingjun Rao, Peipei Zhang, Wenzhong Peng, Yanhui Cui, Jie Chen, Pinhua Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
Nocardia
immunoinformatics
reverse vaccinology (RV)
multi-epitope vaccine
molecular docking
molecular dynamics (MD) simulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1100188/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1100188/full

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