Bacterial Succinoglycans: Structure, Physical Properties, and Applications
Succinoglycan is a type of bacterial anionic exopolysaccharide produced from <i>Rhizobium</i>, <i>Agrobacterium</i>, and other soil bacteria. The exact structure of succinoglycan depends in part on the type of bacterial strain, and the final production yield also depends on t...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/14/2/276 |
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| author | Jae-pil Jeong Yohan Kim Yiluo Hu Seunho Jung |
| author_facet | Jae-pil Jeong Yohan Kim Yiluo Hu Seunho Jung |
| author_sort | Jae-pil Jeong |
| collection | DOAJ |
| description | Succinoglycan is a type of bacterial anionic exopolysaccharide produced from <i>Rhizobium</i>, <i>Agrobacterium</i>, and other soil bacteria. The exact structure of succinoglycan depends in part on the type of bacterial strain, and the final production yield also depends on the medium composition, culture conditions, and genotype of each strain. Various bacterial polysaccharides, such as cellulose, xanthan, gellan, and pullulan, that can be mass-produced for biotechnology are being actively studied. However, in the case of succinoglycan, a bacterial polysaccharide, relatively few reports on production strains or chemical and structural characteristics have been published. Physical properties of succinoglycan, a non-Newtonian and shear thinning fluid, have been reported according to the ratio of substituents (pyruvyl, succinyl, acetyl group), molecular weight (M<sub>w</sub>), and measurement conditions (concentration, temperature, pH, metal ion, etc.). Due to its unique rheological properties, succinoglycan has been mainly used as a thickener and emulsifier in the cosmetic and food industries. However, in recent reports, succinoglycan and its derivatives have been used as functional biomaterials, e.g., in stimuli-responsive drug delivery systems, therapeutics, and cell culture scaffolds. This suggests a new and expanded application of succinoglycan as promising biomaterials in biomedical fields, such as tissue engineering, regenerative medicine, and pharmaceuticals using drug delivery. |
| first_indexed | 2024-03-10T00:39:56Z |
| format | Article |
| id | doaj.art-1160a1ae14174946af5a3da9f4bede33 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-10T00:39:56Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-1160a1ae14174946af5a3da9f4bede332023-11-23T15:08:54ZengMDPI AGPolymers2073-43602022-01-0114227610.3390/polym14020276Bacterial Succinoglycans: Structure, Physical Properties, and ApplicationsJae-pil Jeong0Yohan Kim1Yiluo Hu2Seunho Jung3Department of Bioscience and Biotechnology, Microbial Carbohydrate Resource Bank (MCRB), Konkuk University, Seoul 05029, KoreaDepartment of Bioscience and Biotechnology, Microbial Carbohydrate Resource Bank (MCRB), Konkuk University, Seoul 05029, KoreaDepartment of Bioscience and Biotechnology, Microbial Carbohydrate Resource Bank (MCRB), Konkuk University, Seoul 05029, KoreaDepartment of Bioscience and Biotechnology, Microbial Carbohydrate Resource Bank (MCRB), Konkuk University, Seoul 05029, KoreaSuccinoglycan is a type of bacterial anionic exopolysaccharide produced from <i>Rhizobium</i>, <i>Agrobacterium</i>, and other soil bacteria. The exact structure of succinoglycan depends in part on the type of bacterial strain, and the final production yield also depends on the medium composition, culture conditions, and genotype of each strain. Various bacterial polysaccharides, such as cellulose, xanthan, gellan, and pullulan, that can be mass-produced for biotechnology are being actively studied. However, in the case of succinoglycan, a bacterial polysaccharide, relatively few reports on production strains or chemical and structural characteristics have been published. Physical properties of succinoglycan, a non-Newtonian and shear thinning fluid, have been reported according to the ratio of substituents (pyruvyl, succinyl, acetyl group), molecular weight (M<sub>w</sub>), and measurement conditions (concentration, temperature, pH, metal ion, etc.). Due to its unique rheological properties, succinoglycan has been mainly used as a thickener and emulsifier in the cosmetic and food industries. However, in recent reports, succinoglycan and its derivatives have been used as functional biomaterials, e.g., in stimuli-responsive drug delivery systems, therapeutics, and cell culture scaffolds. This suggests a new and expanded application of succinoglycan as promising biomaterials in biomedical fields, such as tissue engineering, regenerative medicine, and pharmaceuticals using drug delivery.https://www.mdpi.com/2073-4360/14/2/276succinoglycanbacterial polysaccharidesapplicationhydrogelsbiomaterials |
| spellingShingle | Jae-pil Jeong Yohan Kim Yiluo Hu Seunho Jung Bacterial Succinoglycans: Structure, Physical Properties, and Applications Polymers succinoglycan bacterial polysaccharides application hydrogels biomaterials |
| title | Bacterial Succinoglycans: Structure, Physical Properties, and Applications |
| title_full | Bacterial Succinoglycans: Structure, Physical Properties, and Applications |
| title_fullStr | Bacterial Succinoglycans: Structure, Physical Properties, and Applications |
| title_full_unstemmed | Bacterial Succinoglycans: Structure, Physical Properties, and Applications |
| title_short | Bacterial Succinoglycans: Structure, Physical Properties, and Applications |
| title_sort | bacterial succinoglycans structure physical properties and applications |
| topic | succinoglycan bacterial polysaccharides application hydrogels biomaterials |
| url | https://www.mdpi.com/2073-4360/14/2/276 |
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