Differential Effects of Oligosaccharides, Antioxidants, Amino Acids and PUFAs on Heat/Hypoxia-Induced Epithelial Injury in a Caco-2/HT-29 Co-Culture Model

Differential Effects of Oligosaccharides, Antioxidants, Amino Acids and PUFAs on Heat/Hypoxia-Induced Epithelial Injury in a Caco-2/HT-29 Co-Culture Model

(1) Exposure of intestinal epithelial cells to heat and hypoxia causes a (heat) stress response, resulting in the breakdown of epithelial integrity. There are indications that several categories of nutritional components have beneficial effects on maintaining the intestinal epithelial integrity unde...

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Bibliographic Details
Main Authors: Puqiao Lian, Paul A. J. Henricks, Harry J. Wichers, Gert Folkerts, Saskia Braber
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
intestinal epithelial cells
hypoxia
heat stress
epithelial integrity
nutritional components
tight junction
Online Access:https://www.mdpi.com/1422-0067/24/2/1111

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