Prion-like Domains in Spike Protein of SARS-CoV-2 Differ across Its Variants and Enable Changes in Affinity to ACE2

Prion-like Domains in Spike Protein of SARS-CoV-2 Differ across Its Variants and Enable Changes in Affinity to ACE2

Currently, the world is struggling with the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Prions are proteins that possess a unique conformational conversion, with the ability to rapidly shift between multiple conformations due...

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Bibliographic Details
Main Authors: George Tetz, Victor Tetz
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Microorganisms
Subjects:
COVID-19
SARS-CoV-2
variants
prion-like domains
PrD
ACE2
Online Access:https://www.mdpi.com/2076-2607/10/2/280

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