Dosimetry for New Radiation Therapy Approaches Using High Energy Electron Accelerators
We have performed dosimetry studies using electron beams with energies up to 50 MeV, which exceed current clinical energy ranges and approaches the bottom end of the very high energy electron range. 50 MeV electron beams can reach deep-seated tumors. In contrast to photon beams, electron beams can b...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-11-01
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| Series: | Frontiers in Physics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphy.2020.568302/full |
| _version_ | 1828843825974476800 |
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| author | Karolina Kokurewicz Andreas Schüller Enrico Brunetti Anna Subiel Rafael Kranzer Rafael Kranzer Thomas Hackel Markus Meier Ralf-Peter Kapsch Dino A. Jaroszynski |
| author_facet | Karolina Kokurewicz Andreas Schüller Enrico Brunetti Anna Subiel Rafael Kranzer Rafael Kranzer Thomas Hackel Markus Meier Ralf-Peter Kapsch Dino A. Jaroszynski |
| author_sort | Karolina Kokurewicz |
| collection | DOAJ |
| description | We have performed dosimetry studies using electron beams with energies up to 50 MeV, which exceed current clinical energy ranges and approaches the bottom end of the very high energy electron range. 50 MeV electron beams can reach deep-seated tumors. In contrast to photon beams, electron beams can be generated with ultra-high dose rates by linear accelerators, which could enable FLASH radiotherapy of deep-seated tumors. The response of radiochromic film and alanine is compared with dose measurements using an ionisation chamber. Energy dependence is not observed within the measurement uncertainty in the investigated energy range from 15 to 50 MeV. |
| first_indexed | 2024-12-12T20:53:55Z |
| format | Article |
| id | doaj.art-1164d0e9be6547fc8c3519eaf49f8e4b |
| institution | Directory Open Access Journal |
| issn | 2296-424X |
| language | English |
| last_indexed | 2024-12-12T20:53:55Z |
| publishDate | 2020-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physics |
| spelling | doaj.art-1164d0e9be6547fc8c3519eaf49f8e4b2022-12-22T00:12:21ZengFrontiers Media S.A.Frontiers in Physics2296-424X2020-11-01810.3389/fphy.2020.568302568302Dosimetry for New Radiation Therapy Approaches Using High Energy Electron AcceleratorsKarolina Kokurewicz0Andreas Schüller1Enrico Brunetti2Anna Subiel3Rafael Kranzer4Rafael Kranzer5Thomas Hackel6Markus Meier7Ralf-Peter Kapsch8Dino A. Jaroszynski9Department of Physics, SUPA and University of Strathclyde, Glasgow, United KingdomPhysikalisch-Technische Bundesanstalt (PTB), Dosimetry for Radiation Therapy and Diagnostic Radiology, Braunschweig, GermanyDepartment of Physics, SUPA and University of Strathclyde, Glasgow, United KingdomNational Physical Laboratory, Medical Radiation Science, Teddington, United KingdomPhysikalisch-Technische Werkstätten (PTW), R&D, Freiburg, GermanyUniversity Clinic for Medical Radiation Physics, Medical Campus Pius Hospital, Carl von Ossietzky University Oldenburg, Oldenburg, GermanyPhysikalisch-Technische Bundesanstalt (PTB), Dosimetry for Radiation Therapy and Diagnostic Radiology, Braunschweig, GermanyPhysikalisch-Technische Bundesanstalt (PTB), Dosimetry for Radiation Therapy and Diagnostic Radiology, Braunschweig, GermanyPhysikalisch-Technische Bundesanstalt (PTB), Dosimetry for Radiation Therapy and Diagnostic Radiology, Braunschweig, GermanyDepartment of Physics, SUPA and University of Strathclyde, Glasgow, United KingdomWe have performed dosimetry studies using electron beams with energies up to 50 MeV, which exceed current clinical energy ranges and approaches the bottom end of the very high energy electron range. 50 MeV electron beams can reach deep-seated tumors. In contrast to photon beams, electron beams can be generated with ultra-high dose rates by linear accelerators, which could enable FLASH radiotherapy of deep-seated tumors. The response of radiochromic film and alanine is compared with dose measurements using an ionisation chamber. Energy dependence is not observed within the measurement uncertainty in the investigated energy range from 15 to 50 MeV.https://www.frontiersin.org/articles/10.3389/fphy.2020.568302/fullradiochromic filmsdosimetryvery high energy electronsvery high energy electron radiotherapydose-rate independent detectorsalanine dosimetry |
| spellingShingle | Karolina Kokurewicz Andreas Schüller Enrico Brunetti Anna Subiel Rafael Kranzer Rafael Kranzer Thomas Hackel Markus Meier Ralf-Peter Kapsch Dino A. Jaroszynski Dosimetry for New Radiation Therapy Approaches Using High Energy Electron Accelerators Frontiers in Physics radiochromic films dosimetry very high energy electrons very high energy electron radiotherapy dose-rate independent detectors alanine dosimetry |
| title | Dosimetry for New Radiation Therapy Approaches Using High Energy Electron Accelerators |
| title_full | Dosimetry for New Radiation Therapy Approaches Using High Energy Electron Accelerators |
| title_fullStr | Dosimetry for New Radiation Therapy Approaches Using High Energy Electron Accelerators |
| title_full_unstemmed | Dosimetry for New Radiation Therapy Approaches Using High Energy Electron Accelerators |
| title_short | Dosimetry for New Radiation Therapy Approaches Using High Energy Electron Accelerators |
| title_sort | dosimetry for new radiation therapy approaches using high energy electron accelerators |
| topic | radiochromic films dosimetry very high energy electrons very high energy electron radiotherapy dose-rate independent detectors alanine dosimetry |
| url | https://www.frontiersin.org/articles/10.3389/fphy.2020.568302/full |
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