Fecal Volatile Metabolomics Predict Gram-Negative Late-Onset Sepsis in Preterm Infants: A Nationwide Case-Control Study

Fecal Volatile Metabolomics Predict Gram-Negative Late-Onset Sepsis in Preterm Infants: A Nationwide Case-Control Study

Early detection of late-onset sepsis (LOS) in preterm infants is crucial since timely treatment initiation is a key prognostic factor. We hypothesized that fecal volatile organic compounds (VOCs), reflecting microbiota composition and function, could serve as a non-invasive biomarker for preclinical...

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Hlavní autoři: Nina M. Frerichs, Sofia el Manouni el Hassani, Nancy Deianova, Mirjam M. van Weissenbruch, Anton H. van Kaam, Daniel C. Vijlbrief, Johannes B. van Goudoever, Christian V. Hulzebos, Boris. W. Kramer, Esther J. d’Haens, Veerle Cossey, Willem P. de Boode, Wouter J. de Jonge, Alfian N. Wicaksono, James A. Covington, Marc A. Benninga, Nanne K. H. de Boer, Hendrik J. Niemarkt, Tim G. J. de Meij
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2023-02-01
Edice:Microorganisms
Témata:
neonatology
volatile organic compounds
gas chromatography—ion mobility spectrometry
gas chromatography—time of flight—mass spectrometry
fecal biomarker
microbiota
On-line přístup:https://www.mdpi.com/2076-2607/11/3/572

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