Involvement of Epigenetic Mechanisms and Non-coding RNAs in Blood-Brain Barrier and Neurovascular Unit Injury and Recovery After Stroke

Involvement of Epigenetic Mechanisms and Non-coding RNAs in Blood-Brain Barrier and Neurovascular Unit Injury and Recovery After Stroke

Cessation of blood flow leads to a complex cascade of pathophysiological events at the blood-vascular-parenchymal interface which evolves over time and space, and results in damage to neural cells and edema formation. Cerebral ischemic injury evokes a profound and deleterious upregulation in inflamm...

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Bibliographic Details
Main Authors: Svetlana M. Stamatovic, Chelsea M. Phillips, Gabriela Martinez-Revollar, Richard F. Keep, Anuska V. Andjelkovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Neuroscience
Subjects:
blood brain barrier
neurovascular unit
stroke injury
inflammation
DNA methylation
histone deacetylases
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00864/full

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